4.2 Review

Bacteriophages: cancer diagnosis, treatment, and future prospects

Journal

JOURNAL OF PHARMACEUTICAL INVESTIGATION
Volume 51, Issue 1, Pages 23-34

Publisher

SPRINGERNATURE
DOI: 10.1007/s40005-020-00503-x

Keywords

Bacteriophages; Cancer diagnosis; Cancer immunotherapy; Phage therapy

Funding

  1. Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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Early diagnosis is crucial in cancer treatment, but current methods have limitations. Novel technologies, such as the use of bacteriophages, offer potential advantages for cancer diagnosis and treatment. Bacteriophages, with their non-pathogenic nature and genetic engineering capability, may be a promising option for future therapies.
Background Early diagnosis is one of the most important factors in cancer treatment. Unfortunately, despite remarkable advances in the diagnosis and treatment methods of cancers in recent years, these methods are far from being perfect and have significant limitations and disadvantages. High costs and unwanted damage to healthy cells are some of the most important challenges. Area covered With the advent of novel technologies, potentially advantageous methods are being studied actively. The use of bacteriophages is one of the modern methods for cancer diagnosis and treatment. In the present article, we will discuss the potential advantages and limitations regarding the use of bacteriophages in the diagnosis and treatment of malignancies. Expert opinion The use of bacteriophages is one of the more recent methods for cancer diagnosis and treatment. Due to the non-pathogenic nature of bacteriophages, their genetic engineering capability makes them a great option for therapeutic purposes. The exact potential of phages to be used in the diagnosis and treatment of cancer, will be determined with further research in the future.

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