4.7 Article

Positively charged collective oscillations induce efficient Aβ1-42 fibril degradation in the presence of novel Au@Cu2-xS core/shell nanorods

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 52, Pages 6384-6387

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc01470f

Keywords

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Funding

  1. National Natural Science Foundation of China [51872030, 51631001, 51902023, 51702016]
  2. Joint RAMP
  3. D Plan of Hong Kong, Macao, Taiwan, and Beijing [Z191100001619002]
  4. Beijing Institute of Technology Research Fund Program for Young Scholars
  5. Beijing Institute of Technology Analysis and Test Center

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Au@Cu2-xS core/shell nanorods synthesized using a new cation exchange process in ethylene glycol phase exhibit synergistic surface plasmon resonance effects, promoting the capability to degrade A beta 1-42 fibrils into amorphous protein.
We synthesized Au@Cu2-xS core/shell nanorods (NRs) that have synergistic surface plasmon resonance (SPR) effects using a new cation exchange process in ethylene glycol (EG) phase. The dual effect - NIR photothermal and surface positive charge plasmon - of Au@Cu2-xS NRs, promote the capability to degrade A beta 1-42 fibrils into amorphous protein.

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