Journal
INTERNATIONAL NEUROUROLOGY JOURNAL
Volume 25, Issue -, Pages S3-S7Publisher
KOREAN CONTINENCE SOC
DOI: 10.5213/inj.2142174.087
Keywords
Urinary bladder; Fibrosis; Extracellular matrix; Lower urinary tract symptoms; Collagen
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Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [2018R1D1A3B07048492]
- National Research Foundation of Korea [2018R1D1A3B07048492] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Underactive bladder and impaired bladder compliance are irreversible problems associated with bladder fibrosis. Remodeling of the extracellular matrix is considered as an important mechanism in bladder fibrosis. However, various risk factors and conditions contribute to the functional impairment of the bladder due to fibrosis, and there is limited knowledge in the field of neurourology. Further studies are necessary to elucidate the underlying mechanism of bladder fibrosis and to identify effective treatment.
Underactive bladder and impaired bladder compliance are irreversible problems associated with bladder fibrosis. Remodeling of the extracellular matrix is regarded as an important mechanism associated with bladder fibrosis. However, various risk factors and conditions contribute to the functional impairment of the bladder associated with fibrosis, and there is limited knowledge about bladder fibrosis-associated problems in the field of neurourology. Further studies are thus necessary to elucidate the underlying mechanism of bladder fibrosis and to identify effective treatment.
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