Mathematical modelling of lung function - what have we learnt and where to next?

Mathematical modelling has been used in airway and lung physiology with varying degrees of successes. We review recent progress including patient-specific and multi-scale models, ranging from the cellular scale through to tissue and organ scale. We focus on progress in the last three years, but also place that works in a broader historical context. We further comment on the ways in which modelling and experiment interact, and how that might serve the field going forward.

Automated summary

The article reviews the use of mathematical modelling in airway and lung physiology, focusing on recent progress in patient-specific and multi-scale models in the past three years, while also placing these works in a broader historical context. It further discusses the interaction between modelling and experiment, and how this can advance the field in the future.