Journal
EXPERT REVIEW OF PROTEOMICS
Volume 15, Issue 2, Pages 153-164Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14789450.2018.1421072
Keywords
Diet; functional food; gut microbiota; metabolomics; nutraceutical; nutrigenomics; personalized nutrition; proteomics; systems biology; transcriptomics
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Funding
- Regione Toscana-PSR
- grant OPENRICCIO
- Regione Toscana-Bando pubblico per progetti di ricerca nel settore nutraceutica, grant BEERBONE
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Introduction: In the post-genomic era, the opportunity to combine and integrate cutting-edge analytical platforms and data processing systems allowed the birth of foodomics, a discipline that studies the Food and Nutrition domains through the application of advanced omics technologies to improve consumer's well-being, health, and confidence'. Since then, this discipline has rapidly evolved and researchers are now facing the daunting tasks to meet consumers' needs in terms of food traceability, sustainability, quality, safety and integrity. Most importantly, today it is imperative to provide solid evidence of the mechanisms through which food can promote human health and well-being.Areas covered: In this review, the complex relationships connecting food, nutrition and human health will be discussed, with emphasis on the relapses for the development of functional foods and nutraceuticals, personalized nutrition approaches, and the study of the interplay among gut microbiota, diet and health/diseases.Expert commentary: Evidence has been provided supporting the role of various omic platforms in studying the health-promoting effects of food and customized dietary interventions. However, although associated to major analytical challenges, only the proper integration of multi-omics studies and the implementation of bioinformatics tools and databases will help translate findings from clinical practice into effective personalized treatment strategies.
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