Journal
ENDOCRINE
Volume 74, Issue 1, Pages 1-4Publisher
SPRINGER
DOI: 10.1007/s12020-021-02785-z
Keywords
Pituitary adenoma; Neuroendocrine tumor; Pituitary pathology; Acromegaly; Prolactinoma; Cushing disease
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The meeting concluded that the new term PitNETs was not ready for adoption and recommended retaining the term adenoma. It was proposed that a combination of pathological, neuroradiological, and clinical data is essential for defining the aggressiveness/invasion of pituitary adenoma and guiding treatment effectively.
Background In 2017, the International Pituitary Pathology Club proposed to rename pituitary adenoma as pituitary neuroendocrine tumors (PitNETs) but since no consensus on this new terminology was obtained the Pituitary Society decided to host on this topic an international multidisciplinary virtual workshop, Pituitary Neoplasm Nomenclature (PANOMEN), to which several Societies participated with the designation of their representatives in the expert panel. Main conclusion of the meeting was that there was not yet a case for adopting the PitNET nomenclature and main recommendation was that the term adenoma is retained. Aim Aim of this Editorial is to comment the outcome of the recently published document of the meeting. Conclusions Ideally, only the combination of pathological, neuroradiological, and clinical data can define the degree of agressiveness/invasion of a pituitary adenoma and effectively guide treament. This may be classically obtained only with a close multisciplinary collaboration into a PTCOE. It is proposed that improved definition of invasive and aggressive neoplasms may represent the most clinically effective development in the clinico-neuroradiological-pathological denomination and classification of pituitary adenomas.
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