Journal
ARKIVOC
Volume -, Issue -, Pages 273-328Publisher
ARKAT USA INC
DOI: 10.24820/ark.5550190.p011.481
Keywords
Pyrazolone; dihydropyrano[2,3-c]pyrazole; spiro[indoline-3,4-pyrano[2,3-c]pyrazole; aqueous medium; multicomponent reactions
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Funding
- Central University of Gujarat, Gandhinagar, Gujarat, India
- UGC
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Pyrazolone is an important class of heterocyclic compounds with various applications in organic/material/pharmaceutical chemistry, food/textile industry, and cosmetics. The synthesis of biologically active complex molecules by employing pyrazolone has emerged, with dihydropyrano[2,3-c]pyrazoles and spiro-pyrano[2,3-c]pyrazoles holding huge potential in medicinal chemistry due to their wide-ranging biological activities. This review article summarizes recent advances on the application of pyrazolone in multicomponent reactions for the synthesis of dihydro- and spiro-pyrano[2,3-c]pyrazoles in aqueous medium.
Pyrazolone is an important class of heterocyclic compounds with numerous applications in the fields of organic/material/pharmaceutical chemistry, food/textile industry and cosmetics. Because of these importances, the synthesis of biologically active complex molecules by employing pyrazolone has emerged. Dihydropyrano[2,3-c]pyrazoles and spiro-pyrano[2,3-c]pyrazoles are synthesized from pyrazolone and hold huge potential in the field of medicinal chemistry because of their wide-ranging biological activities. This review article will summarize the up to date advances on the application of pyrazolone in multicomponent reactions for the synthesis of dihydro- and spiro-pyrano[2,3-c]pyrazoles in aqueous medium. [GRAPHICS]
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