Journal
MOLECULAR OMICS
Volume 17, Issue 5, Pages 719-724Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1mo00118c
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Funding
- KAUST Smart Health Initiative seeding grants
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In this study, a set of selective and non-selective CPMG-filtered 1D and 2D TOCSY/HSQC experiments were implemented and validated for metabolomics research. These experiments aided in the clear identification of metabolites within complex lipid and protein signals and improved non-targeted analysis by removing background signals in 2D spectra.
Here, we implemented and validated a suite of selective and non-selective CPMG-filtered 1D and 2D TOCSY/HSQC experiments for metabolomics research. They facilitated the unambiguous identification of metabolites embedded in broad lipid and protein signals. The 2D spectra improved non-targeted analysis by removing the background broad signals of macromolecules.
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