4.0 Article

Synthesis of Fused Heterocyclic Systems Derived from 2-Aryl-1,2,3,4-tetrahydroquinolines

Journal

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 57, Issue 5, Pages 793-800

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1070428021050055

Keywords

1; 2; 3; 4-tetrahydroquinolines; cyclization; tetracyclic systems; N-acylation; quinolines; reduction

Funding

  1. Ministry for Education and Science of the Russian Federation [0778-2020-0005]

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This method involves the cyclization of 2-aryl-1,2,3,4-tetrahydroquinolines with triphosgene, chloroacetyl chloride, and oxalyl chloride in the presence of anhydrous AlCl3 in carbon disulfide or dichloroethane, to synthesize fused heterocyclic systems conveniently.
A convenient method of synthesis of fused heterocyclic systems, involving cyclization of the reaction products of 2-aryl-1,2,3,4-tetrahydroquinolines with triphosgene, chloroacetyl chloride, and oxalyl chloride in the presence of anhydrous AlCl3 in carbon disulfide or dichloroethane.

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