Journal
NANOSCALE RESEARCH LETTERS
Volume 16, Issue 1, Pages -Publisher
SPRINGER
DOI: 10.1186/s11671-021-03566-3
Keywords
Bovine serum albumin; All-metal metamaterials; Terahertz; Biosensors
Funding
- National Natural Science Foundation of China [61875251, 61875179]
- Fundamental Research Funds for the Provincial Universities of Zhejiang [2020YW08]
- Outstanding Student Achievement Cultivation Program of China Jiliang University [2019YW27]
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This paper presents a terahertz biosensor based on all-metal metamaterial, with experimental results confirming its high performance in detecting bovine serum albumin. The sensor shows high detection sensitivity and a low limit of detection, making it suitable for various biosensing applications.
In this paper, a terahertz (THz) biosensor based on all-metal metamaterial is theoretically investigated and experimentally verified. This THz metamaterial biosensor uses stainless steel materials that are manufactured via laser-drilling technology. The simulation results show that the maximum refractive index sensitivity and the figure of merit of this metamaterial sensor are 294.95 GHz/RIU and 4.03, respectively. Then, bovine serum albumin was chosen as the detection substance to assess this biosensor's effectiveness. The experiment results show that the detection sensitivity is 72.81 GHz/(ng/mm(2)) and the limit of detection is 0.035 mg/mL. This THz metamaterial biosensor is simple, cost-effective, easy to fabricate, and has great potential in various biosensing applications.
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