4.7 Review

Stimuli-activated molecular photothermal agents for cancer therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 54, Pages 6584-6595

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc02116h

Keywords

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Funding

  1. National Natural Science Foundation of China [21927811, 21874086, 21775094]
  2. National Key R&D Program of China [2019YFA0210100]
  3. Youth Innovation Science and Technology Program of Higher Education Institution of Shandong Province [2019KJC022]

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This review summarizes the recent progress in stimuli-activated molecular photothermal agents (MPTAs) research, including different stimuli, features and challenges, aiming to encourage readers to design and synthesize more efficient MPTAs.
Taking advantage of activatable and imaging-guided properties, stimuli-activated molecular photothermal agents (MPTAs) have drawn great attention in photothermal therapy (PTT) over the past decades. In this review, the recent progress in the study of stimuli-activated MPTAs is summarized from different stimuli, including pH, bioactive small molecules, and enzymes. The features and challenges of stimuli-activated MPTAs are also discussed. This review aims to motivate readers to design and synthesise more efficient MPTAs.

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