4.6 Article

Main interactions of dopamine and risperidone with the dopamine D2 receptor

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Interaction of graphene with antipsychotic drugs: Is there any charge transfer process?

Roxana M. del Castillo et al.

Summary: Antipsychotics are effective in treating schizophrenia due to their interaction with dopamine D2 receptors. The charge transfer process between drugs and receptors differs for agonists and antagonists, with the latter showing more significant charge transfer. This distinction may help differentiate between the two types of drugs.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2021)

Article Chemistry, Physical

Analyzing the interaction energy between dopaminergic agents and DRD2: Is there any difference between risperidone (antagonist), aripiprazole (partial agonist) and pramipexole (agonist)?

Guillermo Goode-Romero et al.

Summary: Dopamine agonists and antagonists are commonly used drugs to control psychosis, with opposite action mechanisms. Risperidone is the only molecule that can replace dopamine at its receptor, explaining its effectiveness in treating schizophrenia symptoms. The electron acceptor capacity of the ligand determines its interaction with the dopamine cavity, providing insights into the action mechanism of these molecules.

COMPUTATIONAL AND THEORETICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease

Osvaldo Yanez et al.

Summary: This study utilized computational models to evaluate potential inhibitors of the SARS-CoV-2 enzyme M-pro, identifying compounds with high affinity that could serve as promising candidates for therapeutic development.

FRONTIERS IN CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Conformational and electronic study of dopamine interacting with the D2 dopamine receptor

Rodrigo D. Tosso et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2020)

Article Multidisciplinary Sciences

New information of dopaminergic agents based on quantum chemistry calculations

Guillermo Goode-Romero et al.

SCIENTIFIC REPORTS (2020)

Review Biochemistry & Molecular Biology

Classics in Chemical Neuroscience: Chlorpromazine

Debra Boyd-Kimball et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Article Chemistry, Medicinal

Implementation of the Molecular Electrostatic Potential over Graphics Processing Units

J. Cesar Cruz et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)

Article Chemistry, Multidisciplinary

Theoretical Study of the Antioxidant Activity of Quercetin Oxidation Products

Alejandro Vasquez-Espinal et al.

FRONTIERS IN CHEMISTRY (2019)

Article Chemistry, Physical

GPUs as boosters to analyze scalar and vector fields in quantum chemistry

Raymundo Hernandez-Esparza et al.

INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

Classics in Chemical Neuroscience: Risperidone

Trevor C. Chopko et al.

ACS CHEMICAL NEUROSCIENCE (2018)

Review Biochemistry & Molecular Biology

Current Concepts and Treatments of Schizophrenia

Piotr Stepnicki et al.

MOLECULES (2018)

Article Pharmacology & Pharmacy

Challenges and opportunities for the development of new antipsychotic drugs

Carlos Forray et al.

BIOCHEMICAL PHARMACOLOGY (2017)

Review Biochemistry & Molecular Biology

Classics in Chemical Neuroscience: Ketamine

Marshall W. Tyler et al.

ACS CHEMICAL NEUROSCIENCE (2017)

Review Chemistry, Medicinal

Dopamine Targeting Drugs for the Treatment of Schizophrenia: Past, Present and Future

Peng Li et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2016)

Review Biochemistry & Molecular Biology

Clozapine, a Fast-Off-D2 Antipsychotic

Philip Seeman

ACS CHEMICAL NEUROSCIENCE (2014)

Article Chemistry, Multidisciplinary

Grid-Based Algorithm to Search Critical Points, in the Electron Density, Accelerated by Graphics Processing Units

Raymundo Hernandez-Esparza et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2014)

Editorial Material Biochemistry & Molecular Biology

Classics in Chemical Neuroscience: Clozapine

Cody J. Wenthur et al.

ACS CHEMICAL NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Homology Modeling of Dopamine D2 and D3 Receptors: Molecular Dynamics Refinement and Docking Evaluation

Chiara Bianca Maria Platania et al.

PLOS ONE (2012)

Article Chemistry, Multidisciplinary

Revealing Noncovalent Interactions

Erin R. Johnson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Biology

A multi-etiology model of systemic degeneration in schizophrenia

Anca Radulescu

JOURNAL OF THEORETICAL BIOLOGY (2009)

Review Chemistry, Medicinal

Emerging opportunities for antipsychotic drug discovery in the postgenomic era

Michael J. Marino et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Psychiatry

Lifetime prevalence of psychotic and bipolar I disorders in a general population

Jonna Perala et al.

ARCHIVES OF GENERAL PSYCHIATRY (2007)

Review Biochemistry & Molecular Biology

Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs

S Miyamoto et al.

MOLECULAR PSYCHIATRY (2005)

Article Multidisciplinary Sciences

The predicted 3D structure of the human D2 dopamine receptor and the binding site and binding affinities for agonists and antagonists

MYS Kalani et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Psychology

Schizophrenia: Etiology and course

E Walker et al.

ANNUAL REVIEW OF PSYCHOLOGY (2004)

Article Pharmacology & Pharmacy

Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors

KD Burris et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)

Review Psychiatry

Atypical antipsychotics: Mechanism of action

P Seeman

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE (2002)

Article Medicine, General & Internal

Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis

J Geddes et al.

BRITISH MEDICAL JOURNAL (2000)