4.6 Review

Sweet Dreams (Are Made of This): A Review and Perspectives on Aspartic Acid Production

Journal

FERMENTATION-BASEL
Volume 7, Issue 2, Pages -

Publisher

MDPI
DOI: 10.3390/fermentation7020049

Keywords

bio-based; bio-chemicals; bio-materials; fermentation; synthesis

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Aspartic acid, or aspartate, is a non-essential amino acid produced and used by the body in two forms: L-aspartic acid and D-aspartic acid, with different roles in protein synthesis and the nervous system. The production and use of aspartic acid have been increasing in recent years.
Aspartic acid, or aspartate, is a non-essential, four carbon amino acid produced and used by the body in two enantiomeric forms: L-aspartic acid and D-aspartic acid. The L-configuration of amino acids is the dominant form used in protein synthesis; thus, L-aspartic acid is by far the more common configuration. However, D-aspartic acid is one of only two known D-amino acids biosynthesized by eukaryotes. While L-aspartic acid is used in protein biosynthesis and neurotransmission, D-aspartic acid is associated with neurogenesis and the endocrine system. Aspartic acid production and use has been growing in recent years. The purpose of this article is to discuss various perspectives on aspartic acid, including its industrial utility, global markets, production and manufacturing, optimization, challenges, and future outlook. As such, this review will provide a thorough background on this key biochemical.

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