Journal
EXERCISE AND SPORT SCIENCES REVIEWS
Volume 45, Issue 1, Pages 24-33Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000095
Keywords
eccentric exercise; muscle damage; lengthening contractions; delayed-onset muscle soreness; muscle strength; muscle adaptation; muscle soreness
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Skeletal muscle adapts to exercise-induced damage by orchestrating several but still poorly understood mechanisms that endow protection from subsequent damage. Known widely as the repeated bout effect, we propose that neural adaptations, alterations to muscle mechanical properties, structural remodeling of the extracellular matrix, and biochemical signaling work in concert to coordinate the protective adaptation.
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