Magnetic particles for multidimensional in vitro bioanalysis

Multidimensional or multiplex bioanalysis represents a crucial approach to improve diagnostic precision, increase assay throughput and advance fundamental discoveries in analytical industry, life science, and nanomedicine. Along this line, bio-interfacing magnetic particles have been playing an important role. Fully exploiting the properties of magnetic particles is the key to tailoring recent technology development for better translational outcomes. In this mini-review, typical magneto-physical dimensions of magnetic particles are introduced. Recent progress of implementing these dimensions with advanced sensor and actuator technologies in multiplex bioanalysis is discussed. Outlooks on potential biomedical applications and challenges are provided.

Automated summary

The use of multidimensional or multiplex bioanalysis is vital for improving diagnostic precision, increasing assay throughput, and driving fundamental discoveries in various fields. Magnetic particles used in bio-interfacing play a critical role in this approach. Efficiently harnessing the properties of magnetic particles is essential in tailoring technology development for better translational outcomes. Recent advancements in integrating the magneto-physical dimensions of magnetic particles with advanced sensor and actuator technologies in multiplex bioanalysis are discussed, along with outlooks on potential biomedical applications and challenges.