4.2 Article

Highly Efficient Near-Infrared Photosensitizers with Aggregation-Induced Emission Characteristics: Rational Molecular Design and Photodynamic Cancer Cell Ablation

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Self-Guiding Polymeric Prodrug Micelles with Two Aggregation-Induced Emission Photosensitizers for Enhanced Chemo-Photodynamic Therapy

Xiaoqing Yi et al.

Summary: The study introduced a self-guiding polymeric micelle for enhanced chemo-photodynamic therapy by utilizing a dual-stage light irradiation strategy, combining two AIE photosensitizers and a reduction-sensitive paclitaxel prodrug. The first light irradiation facilitated cellular uptake, while the second light irradiation led to efficient ROS production and monitored drug release. This dual-stage light irradiation strategy showed superior therapeutic effects compared to continuous light irradiation for only 24 minutes in both in vivo and in vitro studies.

ACS NANO (2021)

Article Multidisciplinary Sciences

Aggregation-induced emission luminogens reveal cell cycle-dependent telomerase activity in cancer cells

Xia Wu et al.

Summary: An AIEgen-based biosensing system was developed to detect telomerase in different cell cycles. The fluorescence signal of cancer cells increased gradually from G0/G1 to S phase, while cancer cells arrested at G2/M phase and normal cells exhibited negligible signal. Compared to normal tissues, malignant tumor samples demonstrated a significant turn-on fluorescence signal.

NATIONAL SCIENCE REVIEW (2021)

Article Chemistry, Multidisciplinary

Molecular Engineering of Near-Infrared-II Photosensitizers with Steric-Hindrance Effect for Image-Guided Cancer Photodynamic Therapy

Shuai Gao et al.

Summary: A new type of photosensitizer was designed in this study, capable of emitting fluorescence in the NIR-II window and producing sufficient singlet oxygen. The nanoparticles demonstrated high efficiency in tumor imaging and photodynamic therapy in mice.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Nanoscience & Nanotechnology

One-for-All Phototheranostic Agent Based on Aggregation-Induced Emission Characteristics for Multimodal Imaging-Guided Synergistic Photodynamic/Photothermal Cancer Therapy

Luqi Liu et al.

Summary: Phototheranostics, a promising direction for modern precision medicine, has attracted considerable attention in cancer research. The design of novel AIE-active fluorogens and versatile nanoparticles has the potential for multimodal imaging-guided synergistic PDT/PTT therapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

Article Chemistry, Multidisciplinary

Improving Image-Guided Surgical and Immunological Tumor Treatment Efficacy by Photothermal and Photodynamic Therapies Based on a Multifunctional NIR AIEgen

Ruming Jiang et al.

Summary: Multimodal therapy using a multifunctional theranostic nanoplatform based on AIEgen enables preoperative diagnosis, intraoperative fluorescence-guided surgery, and photodynamic and photothermal therapies to efficiently kill tumor cells and significantly improve survival rates.

ADVANCED MATERIALS (2021)

Review Chemistry, Multidisciplinary

Recent advances in stimuli-responsive theranostic systems with aggregation-induced emission characteristics

Jing-Jing Hu et al.

Summary: The review summarizes the advancements in stimuli-responsive theranostic systems with AIE characteristics. These systems are classified based on treatment modes and stimuli types, with design strategies and application examples provided. The current state, limitations, and prospects of this technology are also discussed.

AGGREGATE (2021)

Review Chemistry, Multidisciplinary

High-Performance Quinoline-Malononitrile Core as a Building Block for the Diversity-Oriented Synthesis of AIEgens

Zhiqian Guo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Membrane-Anchoring Photosensitizer with Aggregation-Induced Emission Characteristics for Combating Multidrug-Resistant Bacteria

Huan Chen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Medicinal

Aggregation-Induced Emission Photosensitizers: From Molecular Design to Photodynamic Therapy

Jun Dai et al.

JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Tumor-Triggered Disassembly of a Multiple-Agent-Therapy Probe for Efficient Cellular Internalization

Juliang Yang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Review Chemistry, Multidisciplinary

Aggregation-enhanced theranostics: AIE sparkles in biomedical field

Miaomiao Kang et al.

AGGREGATE (2020)

Article Chemistry, Multidisciplinary

Bright red aggregation-induced emission nanoparticles for multifunctional applications in cancer therapy

Liping Zhang et al.

CHEMICAL SCIENCE (2020)

Article Chemistry, Multidisciplinary

Boosting Non-Radiative Decay to Do Useful Work: Development of a Multi-Modality Theranostic System from an AIEgen

Dong Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Biochemical Research Methods

Porphyrin-Based Nanomedicines for Cancer Treatment

Xiangdong Xue et al.

BIOCONJUGATE CHEMISTRY (2019)

Review Chemistry, Multidisciplinary

Aggregation-Induced Emission Luminogens for Activity-Based Sensing

Dong Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Review Chemistry, Multidisciplinary

Efficiency vs. stability: dopant-free hole transporting materials towards stabilized perovskite solar cells

Kasparas Rakstys et al.

CHEMICAL SCIENCE (2019)

Review Chemistry, Multidisciplinary

Aggregation-Induced Emission (AIE) Dots: Emerging Theranostic Nanolights

Guangxue Feng et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

Review Microbiology

Antimicrobial photodynamic therapy - what we know and what we don't

Fabian Cieplik et al.

CRITICAL REVIEWS IN MICROBIOLOGY (2018)

Review Nanoscience & Nanotechnology

All-organic thermally activated delayed fluorescence materials for organic light-emitting diodes

Yuchao Liu et al.

NATURE REVIEWS MATERIALS (2018)

Review Chemistry, Multidisciplinary

Photosensitizers with Aggregation-Induced Emission: Materials and Biomedical Applications

Fang Hu et al.

ADVANCED MATERIALS (2018)

Review Medicine, Research & Experimental

Theranostics based on AIEgens

Dong Wang et al.

THERANOSTICS (2018)

Review Biochemistry & Molecular Biology

New photosensitizers for photodynamic therapy

Heidi Abrahamse et al.

BIOCHEMICAL JOURNAL (2016)

Review Chemistry, Multidisciplinary

Glycosylated Porphyrins, Phthalocyanines, and Other Porphyrinoids for Diagnostics and Therapeutics

Sunaina Singh et al.

CHEMICAL REVIEWS (2015)

Review Chemistry, Multidisciplinary

Aggregation-Induced Emission: Together We Shine, United We Soar!

Ju Mei et al.

CHEMICAL REVIEWS (2015)

Review Chemistry, Multidisciplinary

The triplet excited state of Bodipy: formation, modulation and application

Jianzhang Zhao et al.

CHEMICAL SOCIETY REVIEWS (2015)

Article Chemistry, Multidisciplinary

Multiwfn: A multifunctional wavefunction analyzer

Tian Lu et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Highly efficient organic light-emitting diodes from delayed fluorescence

Hiroki Uoyama et al.

NATURE (2012)

Review Chemistry, Multidisciplinary

The role of porphyrin chemistry in tumor imaging and photodynamic therapy

Manivannan Ethirajan et al.

CHEMICAL SOCIETY REVIEWS (2011)

Article Chemistry, Multidisciplinary

Effect of the Damping Function in Dispersion Corrected Density Functional Theory

Stefan Grimme et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)

Article Chemistry, Medicinal

In Vitro and In Vivo Photocytotoxicity of Boron Dipyrromethene Derivatives for Photodynamic Therapy

Siang Hui Lim et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Chemistry, Physical

Switching luminescent properties in osmium-based β-diketonate complexes

YL Chen et al.

CHEMPHYSCHEM (2005)

Article Chemistry, Multidisciplinary

Highly efficient and photostable photosensitizer based on BODIPY chromophore

T Yogo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)