4.7 Article

Ultrahigh-Speed Spectral-Domain Optical Coherence Tomography up to 1-MHz A-Scan Rate Using Space-Time-Division Multiplexing

Journal

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TIM.2021.3073701

Keywords

Fourier optical signal processing; parallel processing; space-time-division multiplexing (STDM); spectral-domain optical coherence tomography (OCT); ultrahigh-speed imaging system

Funding

  1. Bio & Medical Technology Development Program of the NRF - Korean government (the Ministry of Science, ICT and Future Planning) [2017M3A9E2065282]
  2. Korea Medical Device Development Fund grant - Korea government (Ministry of Science and ICT)
  3. Korea Medical Device Development Fund grant - Korea government (Ministry of Health Welfare)
  4. Korea Medical Device Development Fund grant - Korea government (Ministry of Food and Drug Safety) [KMDF-PR202009010055, 202011C13]
  5. Korea Medical Device Development Fund grant - Korea government (Ministry of Trade, Industry and Energy)

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Researchers developed an ultrahigh-speed SD-OCT system with a 1 MHz A-scan rate using the STDM method, and successfully integrated it with GPU parallel processing to achieve a volume rate of 8 vol/s.
The primary optimization of the imaging speed of optical coherence tomography (OCT) has been keenly studied. In order to overcome the major speed limitation of spectral-domain OCT (SD-OCT), we developed an ultrahigh-speed SD-OCT system, with an A-scan rate of up to 1 MHz, using the method of space-time-division multiplexing (STDM). Multicameras comprising a single spectrometer were implemented in the developed ultrahigh-speed STDM method to eliminate the dead time of operation, whereas STDM was simultaneously employed to enable wide-range scanning measurements at a high speed. By successfully integrating the developed STDM method with GPU parallel processing, 8 vol/s for an image range of 250 x 250 x 2048 pixels (9 x 4.5 x 5 mm) was achieved, with an adjustable volume rate according to the required scanning speed and range. The examined STDM-OCT results of the customized optical thin film confirmed its feasibility for various fields that require rapid and wide-field scanning.

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