4.2 Review

Pediatric Inflammatory Multisystem Syndrome (PIMS) - Potential Role for Cytokines Such Is IL-6

Related references

Note: Only part of the references are listed.
Article Pediatrics

Multi-System Inflammatory Syndrome in a Child Mimicking Kawasaki Disease

Aman Gupta et al.

Summary: There have been reports of severe multi-system hyperinflammatory syndrome resembling Kawasaki disease in children during the current COVID-19 pandemic. Early recognition and treatment are crucial for these patients who have characteristic laboratory parameters and may benefit from immunomodulatory therapy.

JOURNAL OF TROPICAL PEDIATRICS (2021)

Article Pediatrics

Multisystem inflammatory syndrome in children rose and fell with the first wave of the COVID-19 pandemic in France

Ricardo Carbajal et al.

Summary: This study investigated the impact of the COVID-19 pandemic on the occurrence of multisystem inflammatory syndrome in children (MIS-C) and compared its characteristics with Kawasaki disease (KD). The rise and fall of MIS-C cases were strongly correlated with the COVID-19 cases, showing important differences between MIS-C and KD.

ACTA PAEDIATRICA (2021)

Review Pediatrics

COVID-19 and multisystem inflammatory syndrome in children: A systematic review and meta-analysis

Jun Yasuhara et al.

Summary: The study revealed that MIS-C results in multi-organ failure, including gastrointestinal manifestations, myocardial dysfunction, and coronary abnormalities, demonstrating distinct features from Kawasaki disease.

PEDIATRIC PULMONOLOGY (2021)

Review Immunology

Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis

Mejbah Uddin Bhuiyan et al.

Summary: This study reviewed the epidemiological and clinical characteristics of COVID-19 infection in children under five years old, revealing that approximately half of the cases were infants, about half of the cases were asymptomatic, and a small portion required hospitalization. Ongoing surveillance is needed to better understand the transmission and clinical presentation of COVID-19 in young children.

VACCINE (2021)

Review Pediatrics

Multisystem inflammatory syndrome in children related to COVID-19: a systematic review

Levi Hoste et al.

Summary: PIMS-TS/MIS(-C) is a severe, heterogeneous disease with epidemiological enrichment for males, adolescents, and racial and ethnic minorities. Despite its severe presentation, overall short-term outcome is good. The WHO MIS definition is preferred, as it is more precise, while encompassing most cases.

EUROPEAN JOURNAL OF PEDIATRICS (2021)

Review Immunology

Historical overview of the interleukin-6 family cytokine

Sujin Kang et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

Review Virology

COVID-19 epidemic: Disease characteristics in children

Jiatong She et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Review Medicine, Research & Experimental

Organ-specific manifestations of COVID-19 infection

Maria Gavriatopoulou et al.

CLINICAL AND EXPERIMENTAL MEDICINE (2020)

Review Pharmacology & Pharmacy

Targeting STAT3 in cancer and autoimmune diseases

Tohid Gharibi et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2020)

Review Medicine, General & Internal

COVID-19 infection in children and adolescents

Meena Naja et al.

BRITISH JOURNAL OF HOSPITAL MEDICINE (2020)

Article Public, Environmental & Occupational Health

COVID-19-Associated Multisystem Inflammatory Syndrome in Children - United States, March-July 2020

Shana Godfred-Cato et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

Review Pediatrics

Clinical manifestations of children with COVID-19: A systematic review

Tiago H. de Souza et al.

PEDIATRIC PULMONOLOGY (2020)

Review Rheumatology

A roadmap to target interleukin-6 in osteoarthritis

Renske Wiegertjes et al.

RHEUMATOLOGY (2020)

Review Rheumatology

Kawasaki-like disease in children with COVID-19

Ummusen Kaya Akca et al.

RHEUMATOLOGY INTERNATIONAL (2020)

Review Biochemistry & Molecular Biology

Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19

Jan Brabek et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Pediatrics

Hyperinflammatory Syndrome in Children Associated With COVID-19: Need for Awareness

Chandrika S. Bhat et al.

INDIAN PEDIATRICS (2020)

Review Medicine, General & Internal

COVID-19 and Hyperinflammatory Syndrome in Children: Kawasaki Disease with Macrophage Activation Syndrome in Disguise?

Rohit S. Loomba et al.

CUREUS JOURNAL OF MEDICAL SCIENCE (2020)

Review Immunology

Targeting Interleukin-6 Signaling in Clinic

Sujin Kang et al.

IMMUNITY (2019)

Editorial Material Oncology

IL-6, cancer and cachexia: metabolic dysfunction creates the perfect storm

James P. White

TRANSLATIONAL CANCER RESEARCH (2017)

Article Cell Biology

Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity

Thomas R. Flint et al.

CELL METABOLISM (2016)

Review Cell Biology

STAT3 in the systemic inflammation of cancer cachexia

Teresa A. Zimmers et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)

Review Pharmacology & Pharmacy

Kawasaki disease: a comprehensive review of treatment options

Rupal M. Patel et al.

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2015)