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NEW ZEALAND MEDICAL JOURNAL
Volume 134, Issue 1538, Pages 44-51Publisher
NEW ZEALAND MEDICAL ASSOC
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This study found that perceived stress was higher in Parkinson's disease patients during the COVID-19 lockdown, especially in those reporting worsening of tremor, balance/gait, dyskinesia, and bradykinesia. These effects were not modulated by physical activity.
AIMS: Stress plays a key rote in Parkinson's disease (PD) by acting on the dopaminergic system and worsening patients' motor function. The impact of New Zealand's strict lockdown measures to contain COVID-19 on perceived stress and PD motor symptoms remains unknown. Here we examined the relationship between perceived levels of stress, changes in physical activity levels and PD motor symptoms during lockdown. METHODS: During lockdown, 134 participants with PD and 49 controls completed a survey assessing perceived stress, self-reported changes in PD motor symptoms and physical activity duration and intensity prior to and during lockdown. RESULTS: Perceived stress was higher in PD than controls, and in those reporting a worsening of tremor, balance/gait, dyskinesia and bradykinesia compared to those indicating no change during the COVID-19 lockdown. These effects were not modulated by physical activity. CONCLUSIONS: Reducing stressors may be an important adjunct treatment strategy to improve motor function in PD.
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