4.7 Article

Organelle-targeted photothermal agents for cancer therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 57, Issue 63, Pages 7731-7742

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc02168k

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Funding

  1. Hyupsung University

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The article discusses the advancements in organelle-targeted photothermal therapy (PTT) agents for anticancer treatment and provides a structured approach for describing the types and properties of these agents. Representative agents used in the field since 2010 are summarized, along with the latest advances in improving therapeutic efficacy across different types of cancers.
Over the past ten years, advances in the field of organelle-targeted photothermal therapy (PTT) have stimulated the rapid development of organelle-targeted PTT agents as anticancer therapeutic agents. However, to the best of our knowledge, no comprehensive review of organelle-targeted PTT agents has been reported thus far. In this article, we have provided a structured approach for describing the different types and properties of each organelle-targeted PTT agent as well as the potential future therapeutic applications that were classified by their target organelles. Representative agents that have been used in the field of PTT since 2010 have been summarized and the most recent advances in improving the therapeutic efficacy across various types of cancers have also been highlighted.

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