3.8 Review

An Overview of Existing Publications and Most Relevant Projects/Platforms on the Use of Blockchain in Medicine and Neurology

Journal

FRONTIERS IN BLOCKCHAIN
Volume 4, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fbloc.2021.580227

Keywords

blockchain; decentralized ledger technology; platform; neurology; personalized medicine

Funding

  1. National Program of Sustainability II (MEYS CR) [LQ1605]
  2. LF UK [699012]
  3. Grant Agency of Charles University [176317]
  4. Ministry of Education, Youth and Sports of the Czech Republic [PROGRES Q40]
  5. Ministry of Health of the Czech Republic [RVO-FN HK 00179906, FN HK 00179906]
  6. Long-term development plan UHK
  7. MH CZDRO (UHHK) [00179906]
  8. Charles University in Prague, Czechia [PROGRES Q40]
  9. project: PERSONMED-Center for the Development of Personalized Medicine in Age-Related Diseases [CZ.02.1.01/0.0/0.0/17_048/0007441]
  10. ERDF
  11. state budget of the Czechia
  12. National Natural Science Foundation of China [1720108022]

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This article reviews the use of blockchain technology in Medicine and Neurology, highlighting the benefits and potential applications in healthcare. While there are numerous projects related to health care, disease prevention, and healthy lifestyle promotion in medicine, Neurology only has one promising ongoing project. The discussion points out the lack of patient clinical history information as a problem in medicine and suggests that blockchain technology can help with patient management, treatment monitoring, and clinical trial standardization.
Background: Blockchain is a new methodology involving a data structure with list of records, called blocks, which are linked using cryptography. The aim of the review is to overview the existing publication, projects, and platforms on the use of blockchain in Medicine and Neurology. Methods: We searched the bibliographic database of MEDLINE and BASE. We also accessed ICObench, Coinmarketcap, and Mobihealthnews databases to explore upcoming, ongoing, and ended projects. Results: In medicine, there are many projects related to health care, disease prevention, and promotion of healthy life style. In neurology, only one project looks promising: Neuro, an ongoing scientific-technical project uniting scientists, engineers, and programmers for development of new architectures and algorithms of neural networks. Bibliographic searches found 117 publications on Medline and 203 publications on BASE referring to the use of blockchain technology in medicine. Most of them are presented as reviews (narrative, systematic, or minireview), opinions and hypotheses, commentaries, or perspectives. As for Neurology, only one publication refers to the use of blockchain, specifically to Parkinson's disease. Discussion: Among the problems related to medicine, there is the lack of information on the patient's clinical history that could allow accurate diagnosis and treatment. The possibility of having a register based on blockchain technology could help doctors in many ways, including patient management, choosing and monitoring treatments, and standardization of clinical trials. Conclusion: The use of the blockchain technology in medicine has been repetitively proposed to solve different problems. In this article, we highlight the possible benefits of this technology, with attention to Neurology. Blockchain use can lead to quantifiable benefits in the treatment of neurodegenerative diseases, especially in clinical trials that can fail because of an incorrect patient recruitment.

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