SARS-CoV-2 nucleic acid shedding is variable for every person

Introduction: Considering the persistent positivity on RT-qPCR tests, the results of SARS-CoV-2 were monitored to evaluate the viral RNA shedding period. Methods: Between March and June 2020, the sequential results of 29 healthcare workers' were monitored using RT-qPCR. Results: More than 50% of the individuals remained RT-qPCR positive after 14 days. Furthermore, this is the first study to describe positive RT-qPCR for SARS-CoV-2 in a healthcare worker with mild symptoms 95 days after the first positive test. Conclusions: Sequential RT-qPCR results were heterogeneous, and the viral RNA shedding period is unique for each person.

Automated summary

Monitoring the viral RNA shedding period of 29 healthcare workers revealed that over 50% remained RT-qPCR positive after 14 days, with one healthcare worker showing positive results 95 days after the first positive test, indicating heterogeneity in sequential RT-qPCR results and unique viral RNA shedding periods for individuals.