4.6 Article

Role of body temperature variations in bat immune response to viral infections

Journal

JOURNAL OF THE ROYAL SOCIETY INTERFACE
Volume 18, Issue 180, Pages -

Publisher

ROYAL SOC
DOI: 10.1098/rsif.2021.0211

Keywords

bats; interferon-alpha; immunity; virus

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Bats have the ability to coexist with viruses by regulating their body temperature variations between day and night, which prevents viral escape and makes the system more robust.
The ability of bats to coexist with viruses without being harmed is an interesting issue that is still under investigation. Here we use a mathematical model to show that the pattern of body temperature variations observed in bats between day and night is responsible for their ability to keep viruses in check. From the dynamical systems point of view, our model displays an intriguing quasi-periodic behaviour that might be relevant in making the system robust by avoiding viral escape due to perturbations in the body temperature cycle.

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