4.5 Article

Effects of Automation on Sustainability of Immunohistochemistry Laboratory

Journal

HEALTHCARE
Volume 9, Issue 7, Pages -

Publisher

MDPI
DOI: 10.3390/healthcare9070866

Keywords

automated immunostainer; automation; cost reduction; immunohistochemistry

Funding

  1. Ministry of Education, Science and Technological Development of the Republic of Serbia [OI 175047]
  2. Alexander von Humboldt Foundation [3.4-IP-DEU/1019337]
  3. DAAD Foundation [451-03-01858/2013-09/6]

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The COVID-19 pandemic has led to significant changes in the healthcare system, with automation of the IHC procedure reducing time and costs, contributing significantly to the sustainability of the healthcare system during the pandemic by overcoming insufficient human resources.
The COVID-19 pandemic that hit the world recently caused numerous changes affecting the health system in every department. Reduced staff numbers, mostly due to illness, led to an increase in automation at every stage of laboratory work. The immunohistochemistry (IHC) laboratory conducts a high volume of slide staining every day. Therefore, we analyzed time and total costs required to obtain IHC slides in both the manual and automated way, comparing their efficiency by processing the same sample volume (48 microscope slides-the maximum capacity that an automated immunostainer-DAKO, Autostainer Link 48, Part No AS48030-can process over a single cycle). The total IHC procedure time to run 48 slides manually by one technician was 460 min, while the automated process finished a cycle within 390 min (15.22% less time). The final cost of a single manual IHC slide was 12.26 EUR and 7.69 EUR for slides labeled in the automated immunostainer, which reduced final costs by 37.27%. Thus, automation of the IHC procedure reduces the time and costs of the IHC process, contributing significantly to the sustainability of the healthcare system during the COVID-19 pandemic, overcoming insufficient human resources.

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