Journal
CONNECTIVE TISSUE RESEARCH
Volume 56, Issue 4, Pages 265-271Publisher
TAYLOR & FRANCIS INC
DOI: 10.3109/03008207.2015.1040547
Keywords
Cartilage therapy; chondroprogenitor; osteoarthritis; progenitor; stem cell
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Funding
- NIH [P20GM104937]
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Chondroprogenitor cells are a subpopulation of multipotent progenitors that are primed for chondrogenesis. They are believed to have the biological repertoire to be ideal for cell-based cartilage therapy. In addition to summarizing recent advances in chondroprogenitor cell characterization, this review discusses the projected pros and cons of utilizing chondroprogenitors in regenerative medicine and compares them with that of pre-existing methods, including autologous chondrocyte implantation (ACI) and the utilization of bone marrow derived mesenchymal stem cells (MSCs) for the purpose of cartilage tissue repair.
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