Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 9, Issue 36, Pages 7318-7327Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1tb00855b
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Funding
- National Natural Science Foundation of China [51973214]
- ``Thirteenth Five-Year'' Science and Technology Project of Jilin Provincial Department of Education [JJKH20190204KJ]
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Photothermal therapy (PTT) has gained attention in tumor treatment due to its non-invasiveness and little side effects. Boron-dipyrromethene (BODIPY) is widely used in tumor phototherapy, but issues such as low conversion efficiency and short absorption wavelength exist. Latest research focuses on developing BODIPY nanomaterials to enhance PTT effect.
In the past ten years, photothermal therapy (PTT) has attracted widespread attention in tumor treatment due to its non-invasiveness and little side effects. PTT utilizes heat produced by photothermal agents under the irradiation of near-infrared light to kill tumor cells. Boron-dipyrromethene (BODIPY), an organic phototherapy agent, has been widely used in tumor phototherapy due to its higher molar extinction coefficient, robust photostability and good phototherapy effect. However, there are some issues in the application of BODIPY for tumor PTT, such as low photothermal conversion efficiency and short absorption wavelength. In this review, we focus on the latest development of BODIPY nanomaterials for overcoming the above problems and enhancing the PTT effect.
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