Journal
RSC ADVANCES
Volume 11, Issue 42, Pages 26083-26092Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ra05297g
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- Ministero dell'Universita e della Ricerca
- University of Torino
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A chiral heterogeneous catalyst proved to be efficient in a three-component asymmetric Passerini protocol conducted in a deep eutectic solvent. The reaction conditions were mild and environmentally-friendly, with excellent enantioselectivity. The catalyst was easily recovered and reused without any loss in catalytic activity.
A chiral heterogeneous catalyst derivative of (-)-4,5-dimethyl-3,6-bis(1-naphthyl)-1,2-benzenedisulfonimide is proven here to be efficient in a three-component asymmetric Passerini protocol, carried out in a deep eutectic solvent. Reaction conditions are mild and green, while enantioselectivity is excellent. The catalyst was easily recovered and reused with no decrease in its catalytic activity.
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