NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance

SilE and SilB are both proteins involved in the silver efflux pump found in Gram-negative bacteria such as S. typhimurium. Using model peptides along with NMR and CD experiments, we show how SilE may store silver ions prior to delivery and we hypothesize for the first time the interplay between SilB and SilE.

Automated summary

The study demonstrates the role of SilE in storing silver ions and proposes for the first time the interplay between SilB and SilE through experiments using model peptides and techniques such as NMR and CD.