4.6 Review

Molecular diagnostics in the era of COVID-19

Journal

ANALYTICAL METHODS
Volume 13, Issue 34, Pages 3744-3763

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ay00947h

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The review discusses the application of molecular diagnostic technologies in controlling the spread of COVID-19 and the key factors affecting the sensitivity and specificity of the tests used.
As the COVID-19 pandemic continues to escalate globally and acquires new mutations, accurate diagnostic technologies continue to play a vital role in controlling and understanding the epidemiology of this disease. A plethora of technologies have enabled the diagnosis of individuals, informed clinical management, aided population-wide screening to determine transmission rates and identified cases within the wider community and high-risk settings. This review explores the application of molecular diagnostics technologies in controlling the spread of COVID-19, and the key factors that affect the sensitivity and specificity of the tests used.

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