Related references
Note: Only part of the references are listed.Toward the Treatment and Prevention of Alzheimer's Disease: Rational Strategies and Recent Progress
Sam Gandy et al.
ANNUAL REVIEW OF MEDICINE, VOL 64 (2013)
Toward the structure of presenilin/γ-secretase and presenilin homologs
Michael S. Wolfe
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease
Kenghoe Lok et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2013)
Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice
Maria Diaz-Moreno et al.
NEUROBIOLOGY OF AGING (2013)
Characterization of the APP/PS1 mouse model of Alzheimer's disease in senescence accelerated background
Kenghoe Lok et al.
NEUROSCIENCE LETTERS (2013)
Modeling Alzheimer's Disease in Mouse without Mutant Protein Overexpression: Cooperative and Independent Effects of Aβ and Tau
Qinxi Guo et al.
PLOS ONE (2013)
Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease
Ester Aso et al.
BRAIN PATHOLOGY (2012)
The SAMP8 Mouse: A Model to Develop Therapeutic Interventions for Alzheimers Disease
John E. Morley et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Antioxidant Therapies for Alzheimer's Disease
Ye Feng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
The novel object recognition memory: neurobiology, test procedure, and its modifications
M. Antunes et al.
COGNITIVE PROCESSING (2012)
Cerebral Amyloid Angiopathy, Blood-Brain Barrier Disruption and Amyloid Accumulation in SAMP8 Mice
Jaume del Valle et al.
NEURODEGENERATIVE DISEASES (2011)
Three-Amino Acid Spacing of Presenilin Endoproteolysis Suggests a General Stepwise Cleavage of γ-Secretase-Mediated Intramembrane Proteolysis
Akio Fukumori et al.
JOURNAL OF NEUROSCIENCE (2010)
Silencing of CDK5 Reduces Neurofibrillary Tangles in Transgenic Alzheimer's Mice
Diego Piedrahita et al.
JOURNAL OF NEUROSCIENCE (2010)
Activation and intrinsic γ-secretase activity of presenilin 1
Kwangwook Ahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Reassessing the amyloid cascade hypothesis of Alzheimer's disease
Sanjay W. Pimplikar
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Increase in Presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing
Vijaya B. Kumar et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2009)
Senescence-Accelerated Mouse (SAM) with Special References to Neurodegeneration Models, SAMP8 and SAMP10 Mice
Toshio Takeda
NEUROCHEMICAL RESEARCH (2009)
Effects of gonadectomy and hormone replacement on a spontaneous novel object recognition task in adult male rats
T. Aubele et al.
HORMONES AND BEHAVIOR (2008)
Glu332 in the Nicastrin ectodomain is essential for γ-secretase complex maturation but not for its activity
Lucia Chavez-Gutierrez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention
K. Iqbal et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Alzheimer disease, the two-hit hypothesis: An update
Xiongwei Zhu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2007)
Of mice and men: more neurobiology in dementia
Alina Codita et al.
CURRENT OPINION IN PSYCHIATRY (2006)
Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM)
AM Canudas et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
The senescence-accelerated prone mouse (SAMP8): A model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease
DA Butterfield et al.
EXPERIMENTAL GERONTOLOGY (2005)
Alzheimer's disease: the two-hit hypothesis
XW Zhu et al.
LANCET NEUROLOGY (2004)
Mechanism of γ-secretase cleavage activation:: Is γ-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?
KS Knappenberger et al.
BIOCHEMISTRY (2004)
The prevalence and causes of dementia in people under the age of 65 years
RJ Harvey et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2003)
Role of reactive oxygen species in the pathophysiology of human reproduction
A Agarwal et al.
FERTILITY AND STERILITY (2003)
Antibody to amyloid β protein alleviates impaired acquisition, retention, and memory processing in SAMP8 mice
JE Morley et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2002)
Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease
CL Grady et al.
BRAIN (2001)
Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic mice
JJ Lucas et al.
EMBO JOURNAL (2001)
β-Amyloid precursor polypeptide in SAMP8 mice affects learning and memory
JE Morley et al.
PEPTIDES (2000)
Modeling Alzheimer's disease in transgenic mice: effect of age and of Presenilin1 on amyloid biochemistry and pathology in APP/London mice
I Dewachter et al.
EXPERIMENTAL GERONTOLOGY (2000)
Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1
YM Li et al.
NATURE (2000)
How important is oxidative damage? Lessons from Alzheimer's disease
G Perry et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
Share Paper
