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Robert H. I. Andtbacka et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Immune Checkpoint Blockade in Cancer Therapy
Michael A. Postow et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
The Technology and Biology of Single-Cell RNA Sequencing
Aleksandra A. Kolodziejczyk et al.
MOLECULAR CELL (2015)
A global reference for human genetic variation
David M. Altshuler et al.
NATURE (2015)
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
Sachet A. Shukla et al.
NATURE BIOTECHNOLOGY (2015)
Spatial reconstruction of single-cell gene expression data
Rahul Satija et al.
NATURE BIOTECHNOLOGY (2015)
Robust enumeration of cell subsets from tissue expression profiles
Aaron M. Newman et al.
NATURE METHODS (2015)
Computational and analytical challenges in single-cell transcriptomics
Oliver Stegle et al.
NATURE REVIEWS GENETICS (2015)
Development of a high-resolution NGS-based HLA-typing and analysis pipeline
Michael Wittig et al.
NUCLEIC ACIDS RESEARCH (2015)
Adoptive cell transfer as personalized immunotherapy for human cancer
Steven A. Rosenberg et al.
SCIENCE (2015)
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
Amit Zeisel et al.
SCIENCE (2015)
A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells
Beatriz M. Carreno et al.
SCIENCE (2015)
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
Naiyer A. Rizvi et al.
SCIENCE (2015)
Cancer vaccines
Lisa H. Butterfield
BMJ-BRITISH MEDICAL JOURNAL (2015)
HLAreporter: a tool for HLA typing from next generation sequencing data
Yazhi Huang et al.
GENOME MEDICINE (2015)
Cancer vaccines
Lisa H. Butterfield
BMJ-BRITISH MEDICAL JOURNAL (2015)
A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response
Paul F. Robbins et al.
CLINICAL CANCER RESEARCH (2015)
An ensemble approach to accurately detect somatic mutations using SomaticSeq
Li Tai Fang et al.
GENOME BIOLOGY (2015)
OptiType: precision HLA typing from next-generation sequencing data
Andras Szolek et al.
BIOINFORMATICS (2014)
Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads
Yu Bai et al.
BMC GENOMICS (2014)
Deconstructing the Peptide-MHC Specificity of T Cell Recognition
Michael E. Birnbaum et al.
CELL (2014)
Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications
Andy Rimmer et al.
NATURE GENETICS (2014)
Multiplexed ion beam imaging of human breast tumors
Michael Angelo et al.
NATURE MEDICINE (2014)
Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
Charlotte Giesen et al.
NATURE METHODS (2014)
Cancer Immunotherapy Based on Mutation-Specific CD4+T Cells in a Patient with Epithelial Cancer
Eric Tran et al.
SCIENCE (2014)
Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types
Diego Adhemar Jaitin et al.
SCIENCE (2014)
To affinity and beyond: Harnessing the T Cell receptor for cancer immunotherapy
Jessica E. Thaxton et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2014)
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
Pierre G. Coulie et al.
NATURE REVIEWS CANCER (2014)
DeconRNASeq: a statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data
Ting Gong et al.
BIOINFORMATICS (2013)
Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell-mediated antibody-dependent cellular cytotoxicity
Dominika Rudnicka et al.
BLOOD (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
Kristian Cibulskis et al.
NATURE BIOTECHNOLOGY (2013)
Innate and adaptive immune cells in the tumor microenvironment
Thomas F. Gajewski et al.
NATURE IMMUNOLOGY (2013)
Accounting for technical noise in single-cell RNA-seq experiments
Philip Brennecke et al.
NATURE METHODS (2013)
Single-cell sequencing-based technologies will revolutionize whole-organism science
Ehud Shapiro et al.
NATURE REVIEWS GENETICS (2013)
PyroHMMsnp: an SNP caller for Ion Torrent and 454 sequencing data
Feng Zeng et al.
NUCLEIC ACIDS RESEARCH (2013)
An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data
Yuichi Shiraishi et al.
NUCLEIC ACIDS RESEARCH (2013)
Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens
Xiaoming Jia et al.
PLOS ONE (2013)
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue
Michael J. Gerdes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Inferring tumour purity and stromal and immune cell admixture from expression data
Kosuke Yoshihara et al.
NATURE COMMUNICATIONS (2013)
Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers
Qingguo Wang et al.
GENOME MEDICINE (2013)
Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing
Jason O'Rawe et al.
GENOME MEDICINE (2013)
Flow Cytometry Bioinformatics
Kieran O'Neill et al.
PLOS COMPUTATIONAL BIOLOGY (2013)
Single Cell Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
Yvonne Schober et al.
ANALYTICAL CHEMISTRY (2012)
SomaticSniper: identification of somatic point mutations in whole genome sequencing data
David E. Larson et al.
BIOINFORMATICS (2012)
Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs
Christopher T. Saunders et al.
BIOINFORMATICS (2012)
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
Daniel C. Koboldt et al.
GENOME RESEARCH (2012)
Quantitative biology of single neurons
James Eberwine et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2012)
Absolute quantification of somatic DNA alterations in human cancer
Scott L. Carter et al.
NATURE BIOTECHNOLOGY (2012)
HLA techniques: Typing and antibody detection in the laboratory of immunogenetics
Andrea Bontadini
METHODS (2012)
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
Suzanne L. Topalian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets
Andreas Wilm et al.
NUCLEIC ACIDS RESEARCH (2012)
Reliable detection of subclonal single-nucleotide variants in tumour cell populations
Moritz Gerstung et al.
NATURE COMMUNICATIONS (2012)
HLA typing from RNA-Seq sequence reads
Sebastian Boegel et al.
GENOME MEDICINE (2012)
Derivation of HLA types from shotgun sequence datasets
Rene L. Warren et al.
GENOME MEDICINE (2012)
PERT: A Method for Expression Deconvolution of Human Blood Samples from Varied Microenvironmental and Developmental Conditions
Wenlian Qiao et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
The blockade of immune checkpoints in cancer immunotherapy
Drew M. Pardoll
NATURE REVIEWS CANCER (2012)
Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
Paul F. Robbins et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
Maria R. Parkhurst et al.
MOLECULAR THERAPY (2011)
Cancer immunotherapy comes of age
Ira Mellman et al.
NATURE (2011)
Towards a systems understanding of MHC class I and MHC class II antigen presentation
Jacques Neefjes et al.
NATURE REVIEWS IMMUNOLOGY (2011)
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna et al.
GENOME RESEARCH (2010)
MHC Class II epitope predictive algorithms
Morten Nielsen et al.
IMMUNOLOGY (2010)
Origin and evolution of the adaptive immune system: genetic events and selective pressures
Martin F. Flajnik et al.
NATURE REVIEWS GENETICS (2010)
The Sequence Alignment/Map format and SAMtools
Heng Li et al.
BIOINFORMATICS (2009)
Microenvironmental regulation of metastasis
Johanna A. Joyce et al.
NATURE REVIEWS CANCER (2009)
NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11
Claus Lundegaard et al.
NUCLEIC ACIDS RESEARCH (2008)
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
Steven A. Rosenberg et al.
NATURE REVIEWS CANCER (2008)
MALDI imaging mass spectrometry: molecular snapshots of biochemical systems
Dale S. Cornett et al.
NATURE METHODS (2007)
Fluorescence detection of protein clusters in individual cells and tissue sections by using toponome imaging system: sample preparation and measuring procedures
Manuela Friedenberger et al.
NATURE PROTOCOLS (2007)
Analyzing proteome topology and function by automated multidimensional fluorescence microscopy
Walter Schubert et al.
NATURE BIOTECHNOLOGY (2006)
A consensus epitope prediction approach identifies the breadth of murine TCD8+-cell responses to vaccinia virus
Magdalini Moutaftsi et al.
NATURE BIOTECHNOLOGY (2006)
Gene regulation at the single-cell level
N Rosenfeld et al.
SCIENCE (2005)
Identification of tumor antigens and T-cell epitopes, and its clinical application
A Paschen et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2004)
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley et al.
SCIENCE (2002)
ProPred: prediction of HLA-DR binding sites
H Singh et al.
BIOINFORMATICS (2001)
Human leukocyte antigen gene polymorphism and the histocompatibility laboratory
TM Williams
JOURNAL OF MOLECULAR DIAGNOSTICS (2001)