Journal
RSC CHEMICAL BIOLOGY
Volume 2, Issue 5, Pages 1479-1483Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cb00132a
Keywords
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Funding
- Swedish Research Council [VR 2016-04423/VR 2020-04707]
- Swedish Cancer Foundation [19 0347 Pj]
- Science for Life Laboratory
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Investigating microbiome-derived metabolites is crucial for understanding their metabolic interactions with the human host, and there is a need for new methodologies to discover metabolites with unknown bioactivity. In this study, squaric acid is introduced as a new chemoselective moiety for analyzing amine metabolites in human fecal samples.
The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective moiety for amine metabolite analysis in human fecal samples.
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