LEVOFLOXACIN VERSUS CEFIXIME AS AN EMPIRIC TREATMENT IN ACUTE BACTERIAL PROSTATITIS

Acute bacterial prostatitis (ABP) is a clinical condition frequently encountered in clinical practice, but there is a lack of consensus for the diagnosis, investigations, and treatment for this pathology. We have enrolled patients diagnosed with acute prostatitis in three academic urological centres between 2019 - 2020 and followed-up prospectively their evolution under two different frequently used antibiotics-fluoroquinolones and cephalosporins, both combined or not with alpha-blockers. All patients received standard start-up treatment. A total of 154 patients were included. Both groups had similar side effects rates ranging from 8.97% to 11.84%. Both groups had similar positive urine culture 15.38% for group A, respectively 14.47% for group B. Although it is an ongoing study, we can confirm that fluoroquinolones and cephalosporins, with or without alpha-blocker, are as effective and tolerated in enhancing empirical treatment initiated at admission for patients with acute bacterial prostatitis.

Automated summary

The study found that fluoroquinolones and cephalosporins are equally effective and tolerated in treating patients with acute bacterial prostatitis, and both groups showed similar rates of side effects and positive urine culture.