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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
Bruno Costa-Silva et al.
NATURE CELL BIOLOGY (2015)
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
Lucy R. Yates et al.
NATURE MEDICINE (2015)
RNA-mediated epigenetic regulation of gene expression
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Diagnostic Value of Plasma and Urinary 2-Hydroxyglutarate to Identify Patients With Isocitrate Dehydrogenase-Mutated Glioma
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ONCOLOGIST (2015)
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
Kun Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Tissue-based map of the human proteome
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SCIENCE (2015)
Research into cancer metabolomics: Towards a clinical metamorphosis
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SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
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SCIENTIFIC REPORTS (2015)
miR-Test: A Blood Test for Lung Cancer Early Detection
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JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Circulating microRNA Biomarkers as Liquid Biopsy for Cancer Patients: Pros and Cons of Current Assays
Shigeshi Ono et al.
JOURNAL OF CLINICAL MEDICINE (2015)
Machine learning applications in cancer prognosis and prediction
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COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
The national biomarker development alliance: confronting the poor productivity of biomarker research and development
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EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2015)
Combined evaluation of a panel of protein and miRNA serum-exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity
Bindhu Madhavan et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Highly sensitive, non-invasive detection of colorectal cancer mutations using single molecule, third generation sequencing
Giancarlo Russo et al.
APPLIED AND TRANSLATIONAL GENOMICS (2015)
The emerging complexity of gene fusions in cancer
Fredrik Mertens et al.
NATURE REVIEWS CANCER (2015)
The role of 5-hydroxymethylcytosine in human cancer
Gerd P. Pfeifer et al.
CELL AND TISSUE RESEARCH (2014)
Double-stranded DNA in exosomes: a novel biomarker in cancer detection
Caitlin Williams et al.
CELL RESEARCH (2014)
Comparison of serum exosome isolation methods for microRNA profiling
Kadri Rekker et al.
CLINICAL BIOCHEMISTRY (2014)
Molecular profiling of single circulating tumor cells with diagnostic intention
Bernhard Polzer et al.
EMBO MOLECULAR MEDICINE (2014)
Identification of Double-stranded Genomic DNA Spanning All Chromosomes with Mutated KRAS and p53 DNA in the Serum Exosomes of Patients with Pancreatic Cancer
Christoph Kahlert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Metabolomics in cancer biomarker discovery: Current trends and future perspectives
Emily G. Armitage et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2014)
Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration
N. Arraud et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2014)
Plasma mRNA expression levels of BRCA1 and TS as potential predictive biomarkers for chemotherapy in gastric cancer
Jie Shen et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2014)
Proteomics Analysis of Cancer Exosomes Using a Novel Modified Aptamer-based Array (SOMAscanTM) Platform*
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MOLECULAR & CELLULAR PROTEOMICS (2014)
Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry- based Assay Development Using a Fit- for- Purpose Approach
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MOLECULAR & CELLULAR PROTEOMICS (2014)
Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial
Jesus F. San-Miguel et al.
LANCET ONCOLOGY (2014)
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
Jonathan Ledermann et al.
LANCET ONCOLOGY (2014)
Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial
Vanesa Gregorc et al.
LANCET ONCOLOGY (2014)
The validity of circulating microRNAs in oncology: Five years of challenges and contradictions
J. Jarry et al.
MOLECULAR ONCOLOGY (2014)
A draft map of the human proteome
Min-Sik Kim et al.
NATURE (2014)
Mass-spectrometry-based draft of the human proteome
Mathias Wilhelm et al.
NATURE (2014)
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
Jens G. Lohr et al.
NATURE BIOTECHNOLOGY (2014)
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Hyungsoon Im et al.
NATURE BIOTECHNOLOGY (2014)
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
Aaron M. Newman et al.
NATURE MEDICINE (2014)
Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
Jared R. Mayers et al.
NATURE MEDICINE (2014)
The rise of regulatory RNA
Kevin V. Morris et al.
NATURE REVIEWS GENETICS (2014)
Multitarget Stool DNA Testing for Colorectal-Cancer Screening
Thomas F. Imperiale et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Plasma Proteome Database as a resource for proteomics research: 2014 update
Vishalakshi Nanjappa et al.
NUCLEIC ACIDS RESEARCH (2014)
Plasma Septin9 versus Fecal Immunochemical Testing for Colorectal Cancer Screening: A Prospective Multicenter Study
David A. Johnson et al.
PLOS ONE (2014)
Exhaled Breath Analysis for Lung Cancer Detection Using Ion Mobility Spectrometry
Hiroshi Handa et al.
PLOS ONE (2014)
Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma
Francesco Gatto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Identification of plasma protein profiles associated with risk groups of prostate cancer patients
Malin Nordstrom et al.
PROTEOMICS CLINICAL APPLICATIONS (2014)
Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma
Brett E. Johnson et al.
SCIENCE (2014)
Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies
Chetan Bettegowda et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Appraisal of diagnostic ability of UCA1 as a biomarker of carcinoma of the urinary bladder
A. K. Srivastava et al.
TUMOR BIOLOGY (2014)
Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen
Yusuke Yoshioka et al.
NATURE COMMUNICATIONS (2014)
Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy
Hubing Shi et al.
CANCER DISCOVERY (2014)
An Integrated Microfluidic Chip System for Single-Cell Secretion Profiling of Rare Circulating Tumor Cells
Yuliang Deng et al.
SCIENTIFIC REPORTS (2014)
Big Biological Data: Challenges and Opportunities
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GENOMICS PROTEOMICS & BIOINFORMATICS (2014)
PITFALLS AND LIMITATIONS IN TRANSLATION FROM BIOMARKER DISCOVERY TO CLINICAL UTILITY IN PREDICTIVE AND PERSONALISED MEDICINE
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OMICS IN CLINICAL PRACTICE: GENOMICS, PHARMACOGENOMICS, PROTEOMICS, AND TRANSCRIPTOMICS IN CLINICAL RESEARCH (2014)
Five microRNAs in plasma as novel biomarkers for screening of early-stage non-small cell lung cancer
Qing Geng et al.
RESPIRATORY RESEARCH (2014)
The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Jan Van Deun et al.
JOURNAL OF EXTRACELLULAR VESICLES (2014)
Validation of a blood protein signature for non-small cell lung cancer
Michael R. Mehan et al.
CLINICAL PROTEOMICS (2014)
OPINION Challenges in circulating tumour cell research
Catherine Alix-Panabieres et al.
NATURE REVIEWS CANCER (2014)
Reliable Identification of Genomic Variants from RNA-Seq Data
Robert Piskol et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Antibody-independent isolation of circulating tumor cells by continuous-flow dielectrophoresis
Sangjo Shim et al.
BIOMICROFLUIDICS (2013)
Defining piRNA primary transcripts
Xin Zhiguo Li et al.
CELL CYCLE (2013)
SOX17 Promoter Methylation in Circulating Tumor Cells and Matched Cell-Free DNA Isolated from Plasma of Patients with Breast Cancer
Maria Chimonidou et al.
CLINICAL CHEMISTRY (2013)
The Long Journey of Cancer Biomarkers from the Bench to the Clinic
Maria P. Pavlou et al.
CLINICAL CHEMISTRY (2013)
Biomarker Failures
John P. A. Ioannidis
CLINICAL CHEMISTRY (2013)
Multiplex PCR-Based Detection of Circulating Tumor Cells in Lung Cancer Patients Using CK19, PTHrP, and LUNX Specific Primers
Anastasia Katseli et al.
CLINICAL LUNG CANCER (2013)
Ovarian malignancy risk stratification of the adnexal mass using a multivariate index assay
Robert E. Bristow et al.
GYNECOLOGIC ONCOLOGY (2013)
Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma
Alexander Baraniskin et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Circulating cell-free human telomerase reverse transcriptase mRNA in plasma and its potential diagnostic and prognostic value for gastric cancer
Yi Kang et al.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2013)
PCA3 Molecular Urine Test as a Predictor of Repeat Prostate Biopsy Outcome in Men with Previous Negative Biopsies: A Prospective Multicenter Clinical Study
Marc C. Gittelman et al.
JOURNAL OF UROLOGY (2013)
Tumour heterogeneity in the clinic
Philippe L. Bedard et al.
NATURE (2013)
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
Muhammed Murtaza et al.
NATURE (2013)
The Genotype-Tissue Expression (GTEx) project
John Lonsdale et al.
NATURE GENETICS (2013)
Proteoform: a single term describing protein complexity
Lloyd M. Smith et al.
NATURE METHODS (2013)
Tumor Markers in Clinical Practice: A Review Focusing on Common Solid Cancers
Michael J. Duffy
MEDICAL PRINCIPLES AND PRACTICE (2013)
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
K. C. Allen Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients
Xiaohui Ni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
An iPSC Line from Human Pancreatic Ductal Adenocarcinoma Undergoes Early to Invasive Stages of Pancreatic Cancer Progression
Jungsun Kim et al.
CELL REPORTS (2013)
Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping
Malene Jorgensen et al.
JOURNAL OF EXTRACELLULAR VESICLES (2013)
Pitfalls and limitations in translation from biomarker discovery to clinical utility in predictive and personalised medicine
Elisabeth Drucker et al.
EPMA JOURNAL (2013)
Xenobiotic Metabolomics: Major Impact on the Metabolome
Caroline H. Johnson et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
The failure of protein cancer biomarkers to reach the clinic: why, and what can be done to address the problem?
Eleftherios P. Diamandis
BMC MEDICINE (2012)
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Patrick S. Ward et al.
CANCER CELL (2012)
EMT and Dissemination Precede Pancreatic Tumor Formation
Andrew D. Rhim et al.
CELL (2012)
Thymidylate synthase mRNA levels in plasma and tumor as potential predictive biomarkers for raltitrexed sensitivity in gastric cancer
Jie Shen et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
A Multigene Urine Test for the Detection and Stratification of Bladder Cancer in Patients Presenting with Hematuria
Paul O'Sullivan et al.
JOURNAL OF UROLOGY (2012)
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis
Min Yu et al.
NATURE (2012)
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
Daniel Ramskold et al.
NATURE BIOTECHNOLOGY (2012)
Methylome analysis using MeDIP-seq with low DNA concentrations
Oluwatosin Taiwo et al.
NATURE PROTOCOLS (2012)
Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
Bow J. Tauro et al.
METHODS (2012)
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
Marco Gerlinger et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Cell-Free Circulating Plasma hTERT mRNA Is a Useful Marker for Prostate Cancer Diagnosis and Is Associated with Poor Prognosis Tumor Characteristics
Jose A. March-Villalba et al.
PLOS ONE (2012)
Microfluidic Western blotting
Alex J. Hughes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
Tim Forshew et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing
Rebecca J. Leary et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Biospecimens, biomarkers, and burgeoning data: the imperative for more rigorous research standards
George Poste
TRENDS IN MOLECULAR MEDICINE (2012)
Genome-wide DNA Methylation Profiling of Cell-Free Serum DNA in Esophageal Adenocarcinoma and Barrett Esophagus
Rihong Zhai et al.
NEOPLASIA (2012)
Consolidated standards of reporting trials (CONSORT) and the completeness of reporting of randomised controlled trials (RCTs) published in medical journals
Lucy Turner et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2012)
A Review on the Clinical Utility of PSA Cancer Prostate
Mohan Adhyam et al.
INDIAN JOURNAL OF SURGICAL ONCOLOGY (2012)
GC/MS-based metabolomic approach to validate the role of urinary sarcosine and target biomarkers for human prostate cancer by microwave-assisted derivatization
Hao Wu et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2011)
High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number
Benjamin J. Hindson et al.
ANALYTICAL CHEMISTRY (2011)
Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva
Yuko Ogawa et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Biospecimen Reporting for Improved Study Quality
Helen M. Moore et al.
BIOPRESERVATION AND BIOBANKING (2011)
Diagnosis of lung cancer in individuals with solitary pulmonary nodules by plasma microRNA biomarkers
Jun Shen et al.
BMC CANCER (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Increased Selectivity, Analytical Precision, and Throughput in Targeted Proteomics
Reiko Kiyonami et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Non-coding RNAs in human disease
Manel Esteller
NATURE REVIEWS GENETICS (2011)
Diagnostic performance of the PCA3 urine test
George Leighton Lee et al.
NATURE REVIEWS UROLOGY (2011)
Circulating Serologic and Molecular Biomarkers in Malignant Melanoma
Shanique R. Palmer et al.
MAYO CLINIC PROCEEDINGS (2011)
Effectiveness of a Multivariate Index Assay in the Preoperative Assessment of Ovarian Tumors
Frederick R. Ueland et al.
OBSTETRICS AND GYNECOLOGY (2011)
Haemolysis during Sample Preparation Alters microRNA Content of Plasma
Michaela B. Kirschner et al.
PLOS ONE (2011)
Plasma Free Amino Acid Profiling of Five Types of Cancer Patients and Its Application for Early Detection
Yohei Miyagi et al.
PLOS ONE (2011)
Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases
Anders Carlsson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Detection and quantification of rare mutations with massively parallel sequencing
Isaac Kinde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A Perspective on Cancer Cell Metastasis
Christine L. Chaffer et al.
SCIENCE (2011)
Effect of Collision Energy Optimization on the Measurement of Peptides by Selected Reaction Monitoring (SRM) Mass Spectrometry
Brendan MacLean et al.
ANALYTICAL CHEMISTRY (2010)
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection
Shawn A. Ritchie et al.
BMC MEDICINE (2010)
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial
Tanja Fehm et al.
BREAST CANCER RESEARCH AND TREATMENT (2010)
The Clinical Plasma Proteome: A Survey of Clinical Assays for Proteins in Plasma and Serum
N. Leigh Anderson
CLINICAL CHEMISTRY (2010)
Peptides Generated Ex Vivo from Serum Proteins by Tumor-Specific Exopeptidases Are Not Useful Biomarkers in Ovarian Cancer
John F. Timms et al.
CLINICAL CHEMISTRY (2010)
A Recipe for Proteomics Diagnostic Test Development: The OVA1 Test, from Biomarker Discovery to FDA Clearance
Eric T. Fung
CLINICAL CHEMISTRY (2010)
Sarcosine in Urine after Digital Rectal Examination Fails as a Marker in Prostate Cancer Detection and Identification of Aggressive Tumours
Florian Jentzmik et al.
EUROPEAN UROLOGY (2010)
Cancer Biomarkers: Can We Turn Recent Failures into Success?
Eleftherios P. Diamandis
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Optical and non-optical methods for detection and characterization of microparticles and exosomes
E. van der Pol et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2010)
International network of cancer genome projects
Thomas J. Hudson et al.
NATURE (2010)
Taking a new biomarker into routine use - A perspective from the routine clinical biochemistry laboratory
Catharine Sturgeon et al.
PROTEOMICS CLINICAL APPLICATIONS (2010)
Microfiltration isolation of human urinary exosomes for characterization by MS
Michael L. Merchant et al.
PROTEOMICS CLINICAL APPLICATIONS (2010)
Clinical validity: Defining biomarker performance
Patrick M. M. Bossuyt
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2010)
Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer
Shannon L. Stott et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Serum sarcosine is not a marker for prostate cancer
Eduard A. Struys et al.
ANNALS OF CLINICAL BIOCHEMISTRY (2010)
Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients withMetastaticBreast Colorectal and Prostate Cancer
M. Craig Miller et al.
JOURNAL OF ONCOLOGY (2010)
Screening for prostate cancer: systematic review and meta-analysis of randomised controlled trials
Mia Djulbegovic et al.
BMJ-BRITISH MEDICAL JOURNAL (2010)
Serum Carcinoembryonic Antigen Monitoring After Curative Resection for Colorectal Cancer: Clinical Significance of the Preoperative Level
In Ja Park et al.
ANNALS OF SURGICAL ONCOLOGY (2009)
Plasma amino acid analysis for diagnosis and amino acid-based metabolic networks
Takeshi Kimura et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2009)
LDH correlation with survival in advanced melanoma from two large, randomised trials (Oblimersen GM301 and EORTC 18951)
Sanjiv S. Agarwala et al.
EUROPEAN JOURNAL OF CANCER (2009)
Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers
Mi Ran Kang et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Angiogenin cleaves tRNA and promotes stress-induced translational repression
Satoshi Yamasaki et al.
JOURNAL OF CELL BIOLOGY (2009)
The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry
Andrew N. Hoofnagle et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
Pierre Fenaux et al.
LANCET ONCOLOGY (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
Arun Sreekumar et al.
NATURE (2009)
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma
Terri A. Addona et al.
NATURE BIOTECHNOLOGY (2009)
A HUPO test sample study reveals common problems in mass spectrometry-based proteomics
Alexander W. Bell et al.
NATURE METHODS (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Real-Time DNA Sequencing from Single Polymerase Molecules
John Eid et al.
SCIENCE (2009)
Diagnostic precision of carcinoembryonic antigen in the detection of recurrence of colorectal cancer
Emile Tan et al.
SURGICAL ONCOLOGY-OXFORD (2009)
Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot study
M. Westhoff et al.
THORAX (2009)
Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
Charles H. Lawrie et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
A multicenter evaluation of the PCA3 molecular urine test: Pre-analytical effects, analytical performance, and diagnostic accuracy
Lori J. Sokoll et al.
CLINICA CHIMICA ACTA (2008)
Development of a multiplex RNA urine test for the detection and stratification of transitional cell carcinoma of the bladder
Andrew Holyoake et al.
CLINICAL CANCER RESEARCH (2008)
Analysis of mutations in DNA isolated from plasma and stool of colorectal cancer patients
Frank Diehl et al.
GASTROENTEROLOGY (2008)
Pivotal Evaluation of the Accuracy of a Biomarker Used for Classification or Prediction: Standards for Study Design
Margaret S. Pepe et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
Lung cancer screening with low-dose computed tomography: A non-invasive diagnostic protocol for baseline lung nodules
Giulia Veronesi et al.
LUNG CANCER (2008)
MicroRNAs accurately identify cancer tissue origin
Nitzan Rosenfeld et al.
NATURE BIOTECHNOLOGY (2008)
Circulating mutant DNA to assess tumor dynamics
Frank Diehl et al.
NATURE MEDICINE (2008)
Reverse-phase protein lysate microarrays for cell signaling analysis
Brett Spurrier et al.
NATURE PROTOCOLS (2008)
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
Christos S. Karapetis et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Detection of pancreatic cancer using antibody microarray-based serum protein profiling
Johan Ingvarsson et al.
PROTEOMICS (2008)
Divergent Transcription from Active Promoters
Amy C. Seila et al.
SCIENCE (2008)
KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab
W. De Roock et al.
ANNALS OF ONCOLOGY (2008)
Circulating tumor cell number and prognosis in progressive castration-resistant prostate cancer
Daniel C. Danila et al.
CLINICAL CANCER RESEARCH (2007)
Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays
Michael E. Hudson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The needle in the haystack: Application of breast fine-needle aspirate samples to quantitative protein microarray technology
Amy Rapkiewicz et al.
CANCER CYTOPATHOLOGY (2007)
RNA maps reveal new RNA classes and a possible function for pervasive transcription
Philipp Kapranov et al.
SCIENCE (2007)
Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: A multicohort cross-institutional study
Fumiko Taguchi et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Circulating free DNA in plasma or serum as biomarker of carcinogenesis: Practical aspects and biological significance
Emmanuelle Gormally et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2007)
Role of tumor markers in patients with solid cancers: A critical review
Michael J. Duffy
EUROPEAN JOURNAL OF INTERNAL MEDICINE (2007)
Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks
Alejandro Wolf-Yadlin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The classification, functions and clinical use of different isoforms of HCG
Ulf-Hakan Stenman et al.
HUMAN REPRODUCTION UPDATE (2006)
MicroRNA signatures in human cancers
George A. Calin et al.
NATURE REVIEWS CANCER (2006)
APTIMA PCA3 molecular urine test: Development of a method to aid in the diagnosis of prostate cancer
Jack Groskopf et al.
CLINICAL CHEMISTRY (2006)
Detection and quantification of mutations in the plasma of patients with colorectal tumors
F Diehl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Exosomal-like vesicles are present in human blood plasma
MP Caby et al.
INTERNATIONAL IMMUNOLOGY (2005)
Serum protein markers for early detection of ovarian cancer
G Mor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Innovation - Detection and interpretation of altered methylation patterns in cancer cells
T Ushijima
NATURE REVIEWS CANCER (2005)
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
H Suzuki et al.
NATURE GENETICS (2004)
Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments
KA Baggerly et al.
BIOINFORMATICS (2004)
Circulating tumor cells, disease progression, and survival in metastatic breast cancer
M Cristofanilli et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Quantitative metabolome analysis using capillary electrophoresis mass spectrometry
T Soga et al.
JOURNAL OF PROTEOME RESEARCH (2003)
A data review and re-assessment of ovarian cancer serum proteomic profiling
JM Sorace et al.
BMC BIOINFORMATICS (2003)
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history:: A combined analysis of 22 studies
A Antoniou et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
Chromosomal instability and tumors promoted by DNA hypomethylation
A Eden et al.
SCIENCE (2003)
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors
WY Chen et al.
NATURE GENETICS (2003)
The STARD statement for reporting studies of diagnostic accuracy: Explanation and elaboration
PM Bossuyt et al.
CLINICAL CHEMISTRY (2003)
Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics
VV Tolstikov et al.
ANALYTICAL CHEMISTRY (2003)
Use of proteomic patterns in serum to identify ovarian cancer
EF Petricoin et al.
LANCET (2002)
Serum heterophile antibodies interfere with prostate specific antigen test and result in over treatment in a patient with prostate cancer
BR Morgan et al.
JOURNAL OF UROLOGY (2001)
Global analysis of protein activities using proteome chips
H Zhu et al.
SCIENCE (2001)
The value of Ca 125 in the evaluation of tuberculosis activity
A Yilmaz et al.
RESPIRATORY MEDICINE (2001)
Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
CP Paweletz et al.
ONCOGENE (2001)
Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry
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