Journal
BIOINFORMATICS AND BIOLOGY INSIGHTS
Volume 15, Issue -, Pages -Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/11779322211035921
Keywords
Big data; cloud computing; multi-omics data; data analytics; data integration
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Funding
- Ministry of Electronics and Information Technology (MeitY), Government of India
- National Institute for Health Research (NIHR) Birmingham Experimental Cancer Medicine Centre (ECMC)
- NIHR Birmingham Surgical Reconstruction and Microbiology Research Centre (SRMRC)
- Nanocommons H2020-EU [731032]
- NIHR Birmingham Biomedical Research Centre
- MRC (Medical Research Council) Health Data Research UK [HDRUK/CFC/01]
- UK Research and Innovation
- Department of Health and Social Care (England)
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High-throughput experiments allow researchers to explore complex multifactorial diseases through large-scale analysis of omics data. Cloud computing is proving increasingly useful in molecular modeling, omics data analytics, and the integration, analysis, and interpretation of phenotypic data. Recent innovations in computational technologies, especially in cloud computing, offer a promising, low-cost, and highly flexible solution for processing and analyzing omics data.
High-throughput experiments enable researchers to explore complex multifactorial diseases through large-scale analysis of omics data. Challenges for such high-dimensional data sets include storage, analyses, and sharing. Recent innovations in computational technologies and approaches, especially in cloud computing, offer a promising, low-cost, and highly flexible solution in the bioinformatics domain. Cloud computing is rapidly proving increasingly useful in molecular modeling, omics data analytics (eg, RNA sequencing, metabolomics, or proteomics data sets), and for the integration, analysis, and interpretation of phenotypic data. We review the adoption of advanced cloud-based and big data technologies for processing and analyzing omics data and provide insights into state-of-the-art cloud bioinformatics applications.
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