Journal
KOREAN JOURNAL OF RADIOLOGY
Volume 22, Issue 5, Pages 677-687Publisher
KOREAN RADIOLOGICAL SOC
DOI: 10.3348/kjr.2020.1166
Keywords
Breast; Ultrasound; Ultrasonography; Microvascular imaging; Contrast agent; Radiogenomics; Radiomics
Funding
- National Research Foundation of Korea (NRF) - Korea government (Ministry of Science and ICT) [NRF-2020R1F1A1073213]
- Korea University grant [K2008291]
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Microvascular ultrasound (US) techniques offer high sensitivity and spatial resolution for detailed visualization of low-flow vessels and are used in breast lesion evaluation. Microvascular US imaging with contrast agents can amplify flow signals, facilitating hemodynamic evaluation of breast lesions.
Microvascular ultrasound (US) techniques are advanced Doppler techniques that provide high sensitivity and spatial resolution for detailed visualization of low-flow vessels. Microvascular US imaging can be applied to breast lesion evaluation with or without US contrast agents. Microvascular US imaging without a contrast agent uses a sophisticated wall filtering system to selectively obtain low-flow Doppler signals from overlapped artifacts. Microvascular US imaging with second-generation contrast agents amplifies flow signals and makes them last longer, which facilitates hemodynamic evaluation of breast lesions. In this review article, we will introduce various microvascular US techniques, explain their clinical applications in breast cancer diagnosis and radiologic-histopathologic correlation, and provide a summary of a recent radiogenomic study using microvascular US.
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