Related references
Note: Only part of the references are listed.COVID-19 and the cardiovascular system
Ying-Ying Zheng et al.
NATURE REVIEWS CARDIOLOGY (2020)
The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane
Chun-Che Tseng et al.
PLOS ONE (2020)
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Renhong Yan et al.
SCIENCE (2020)
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp et al.
SCIENCE (2020)
Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy
Gabriela N. Algarroba et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2020)
Autopsy Findings and Venous Thromboembolism in Patients With COVID-19
Dominic Wichmann et al.
ANNALS OF INTERNAL MEDICINE (2020)
Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N=4532)
M. Montopoli et al.
ANNALS OF ONCOLOGY (2020)
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
Qihui Wang et al.
CELL (2020)
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
Ren-Di Jiang et al.
CELL (2020)
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients
Pierre Bost et al.
CELL (2020)
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
Alexandra C. Walls et al.
CELL (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
CELL (2020)
SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells
Soeren Lukassen et al.
EMBO JOURNAL (2020)
Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection
David Baud et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)
Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways
Anne Harbig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Cell entry mechanisms of SARS-CoV-2
Jian Shang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
SARS-CoV-2 productively infects human gut enterocytes
Mart M. Lamers et al.
SCIENCE (2020)
SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses
Marco R. Straus et al.
VIROLOGY (2020)
SARS-CoV-2 and viral sepsis: observations and hypotheses
Hui Li et al.
LANCET (2020)
Impact of sex and gender on COVID-19 outcomes in Europe
Catherine Gebhard et al.
BIOLOGY OF SEX DIFFERENCES (2020)
Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from the periphery to the brain
Zhengqian Li et al.
FRONTIERS OF MEDICINE (2020)
Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China
Shaobo Shi et al.
JAMA CARDIOLOGY (2020)
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Jun Lan et al.
NATURE (2020)
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
David E. Gordon et al.
NATURE (2020)
Structural basis of receptor recognition by SARS-CoV-2
Jian Shang et al.
NATURE (2020)
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
Waradon Sungnak et al.
NATURE MEDICINE (2020)
Kidney involvement in COVID-19 and rationale for extracorporeal therapies
Claudio Ronco et al.
NATURE REVIEWS NEPHROLOGY (2020)
Multiorgan and Renal Tropism of SARS-CoV-2
Victor G. Puelles et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
Ruochen Zang et al.
SCIENCE IMMUNOLOGY (2020)
Gender Differences in Patients With COVID-19: Focus on Severity and Mortality
Jian-Min Jin et al.
FRONTIERS IN PUBLIC HEALTH (2020)
Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease
Ce Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
Benjamin T. Bradley et al.
LANCET (2020)
Determinants of COVID-19 disease severity in patients with cancer
Elizabeth V. Robilotti et al.
NATURE MEDICINE (2020)
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis
Chun-Jung Ko et al.
ONCOGENE (2020)
Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis
F. A. Klok et al.
THROMBOSIS RESEARCH (2020)
Transplacental transmission of SARS-CoV-2 infection
Alexandre J. Vivanti et al.
NATURE COMMUNICATIONS (2020)
SARS-CoV-2 infection of the placenta
Hillary Hosier et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Membrane-Anchored Serine Proteases and Protease-Activated Receptor-2-Mediated Signaling: Co-Conspirators in Cancer Progression
Nisha R. Pawar et al.
CANCER RESEARCH (2019)
Blocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors
Trine Tamberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
Leonard Drees et al.
PLOS GENETICS (2019)
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1
Pawel Zmora et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells
Adam L. Vanarsdall et al.
MBIO (2018)
Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors
Kayla M. Coffin et al.
CELL HOST & MICROBE (2018)
Sexual transmission of Zika virus and other flaviviruses: A living systematic review
Michel Jacques Counotte et al.
PLOS MEDICINE (2018)
Persistence and Sexual Transmission of Filoviruses
Brayden G. Schindell et al.
VIRUSES-BASEL (2018)
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
Barrett L. Updegraff et al.
CELL REPORTS (2018)
The role of type II transmembrane serine protease-mediated signaling in cancer
Lauren M. Tanabe et al.
FEBS JOURNAL (2017)
The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition
Min Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and-2-mediated cell-surface localization
Andrew S. Murray et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion
Alexandra C. Walls et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Yuan Yuan et al.
NATURE COMMUNICATIONS (2017)
Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2
Frank Shiao et al.
PLOS ONE (2017)
The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells
Shang-Ru Wu et al.
SCIENTIFIC REPORTS (2017)
The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover
David J. Wilkinson et al.
SCIENTIFIC REPORTS (2017)
Matriptase zymogen supports epithelial development, homeostasis and regeneration
Stine Friis et al.
BMC BIOLOGY (2017)
Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling
Sylvain M. Le Gall et al.
BLOOD (2016)
En Route to New Therapeutic Options for Iron Overload Diseases: Matriptase-2 as a Target for Kunitz-Type Inhibitors
Anna-Madeleine Beckmann et al.
CHEMBIOCHEM (2016)
Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN
Zebin Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
Nora Kuehn et al.
JOURNAL OF VIROLOGY (2016)
TMPRSS12 Is an Activating Protease for Subtype B Avian Metapneumovirus
Bingling Yun et al.
JOURNAL OF VIROLOGY (2016)
Pre-fusion structure of a human coronavirus spike protein
Robert N. Kirchdoerfer et al.
NATURE (2016)
Coronaviruses - drug discovery and therapeutic options
Alimuddin Zumla et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin
Jason Z. Niehaus et al.
BIOCHEMISTRY (2015)
Discovery of O-(3-carbamimidoylphenyl)-L-serine amides as matriptase inhibitors using a fragment-linking approach
Rajeev Goswami et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)
Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis
Chun-Jung Ko et al.
CANCER RESEARCH (2015)
Proteolytic Activation of the Protease-activated Receptor (PAR)-2 by the Glycosylphosphatidylinositol-anchored Serine Protease Testisin
Kathryn H. Driesbaugh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
TMPRSS4 induces cancer cell invasion through pro-uPA processing
Hye-Jin Min et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy
Rajeev Goswami et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
The Protease Inhibitor HAI-2, but Not HAI-1, Regulates Matriptase Activation and Shedding through Prostasin
Stine Friis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein
Adeline Heurich et al.
JOURNAL OF VIROLOGY (2014)
TMPRSS2 Is a Host Factor That Is Essential for Pneumotropism and Pathogenicity of H7N9 Influenza A Virus in Mice
Carolin Tarnow et al.
JOURNAL OF VIROLOGY (2014)
Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization
Sandra C. Bernard et al.
NATURE MEDICINE (2014)
Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA
Tania Fontanil et al.
ONCOLOGY REPORTS (2014)
Functional Analysis of a Missense Mutation in the Serine Protease Inhibitor SPINT2 Associated with Congenital Sodium Diarrhea
Nicolas Faller et al.
PLOS ONE (2014)
Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries
Olivier Barre et al.
PLOS ONE (2014)
Three monoclonal antibodies against the serpin protease nexin-1 prevent protease translocation
Tina M. Kousted et al.
THROMBOSIS AND HAEMOSTASIS (2014)
Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2
Eva Maurer et al.
BIOCHEMICAL JOURNAL (2013)
Crystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1
Baoyu Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A Matriptase-Prostasin Reciprocal Zymogen Activation Complex with Unique Features PROSTASIN AS A NON-ENZYMATIC CO-FACTOR FOR MATRIPTASE ACTIVATION
Stine Friis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Matriptase, HAT, and TMPRSS2 Activate the Hemagglutinin of H9N2 Influenza A Viruses
Joanna Baron et al.
JOURNAL OF VIROLOGY (2013)
Matriptase Proteolytically Activates Influenza Virus and Promotes Multicycle Replication in the Human Airway Epithelium
Alexandre Beaulieu et al.
JOURNAL OF VIROLOGY (2013)
TMPRSS2 Is an Activating Protease for Respiratory Parainfluenza Viruses
Masako Abe et al.
JOURNAL OF VIROLOGY (2013)
Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors
Rajeev Goswami et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation
Summer E. Galloway et al.
PLOS PATHOGENS (2013)
Allosteric antibody inhibition of human hepsin protease
Tobias Koschubs et al.
BIOCHEMICAL JOURNAL (2012)
Hepatocyte growth factor activator inhibitor type 1 inhibits protease activity and proteolytic activation of human airway trypsin-like protease
Minoru Kato et al.
JOURNAL OF BIOCHEMISTRY (2012)
A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies
Eric L. Schneider et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency-Associated Developmental Defects by Preventing Matriptase Activation
Roman Szabo et al.
PLOS GENETICS (2012)
Membrane-Anchored Serine Proteases in Vertebrate Cell and Developmental Biology
Roman Szabo et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Peptide Length and Leaving-Group Sterics Influence Potency of Peptide Phosphonate Protease Inhibitors
Christopher M. Brown et al.
CHEMISTRY & BIOLOGY (2011)
A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry
Ana Shulla et al.
JOURNAL OF VIROLOGY (2011)
Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease
Stephanie Bertram et al.
JOURNAL OF VIROLOGY (2011)
Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum
Cecile Crosnier et al.
NATURE (2011)
Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1
Cai Yuan et al.
BMC STRUCTURAL BIOLOGY (2011)
Matriptase Is a Novel Initiator of Cartilage Matrix Degradation in Osteoarthritis
Jennifer M. Milner et al.
ARTHRITIS AND RHEUMATISM (2010)
Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA
Kate A. Owen et al.
BIOCHEMICAL JOURNAL (2010)
Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo
Eric Camerer et al.
DEVELOPMENTAL CELL (2010)
TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor
Tomio Hashimoto et al.
FEBS JOURNAL (2010)
Regulation of the Matriptase-Prostasin Cell Surface Proteolytic Cascade by Hepatocyte Growth Factor Activator Inhibitor-1 during Epidermal Differentiation
Ya-Wen Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Novel Type II Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of the Hemagglutinin of Highly Pathogenic Avian Influenza Viruses and Induce Their Multicycle Replication
Yuushi Okumura et al.
JOURNAL OF VIROLOGY (2010)
Pegylated Kunitz Domain Inhibitor Suppresses Hepsin-Mediated Invasive Tumor Growth and Metastasis
Wei Li et al.
CANCER RESEARCH (2009)
Hepatocyte Growth Factor Activator Inhibitor Type 1 Regulates Epithelial to Mesenchymal Transition through Membrane-Bound Serine Proteinases
Haixia Cheng et al.
CANCER RESEARCH (2009)
Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice
Roman Szabo et al.
DEVELOPMENT (2009)
Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides
Francois Beliveau et al.
FEBS JOURNAL (2009)
Type II Transmembrane Serine Proteases
Thomas H. Bugge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Proteolytic Activation of the 1918 Influenza Virus Hemagglutinin
Chawaree Chaipan et al.
JOURNAL OF VIROLOGY (2009)
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
Sandrine Belouzard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations
Glen Spraggon et al.
PROTEIN SCIENCE (2009)
Type II transmembrane serine proteases in cancer and viral infections
So-Young Choi et al.
TRENDS IN MOLECULAR MEDICINE (2009)
Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design
David C. Tully et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Type II transmembrane serine proteases in development and disease
Roman Szabo et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Structure of Human Prostasin, a Target for the Regulation of Hypertension
Keith W. Rickert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Potent Inhibition and Global Co-localization Implicate the Transmembrane Kunitz-type Serine Protease Inhibitor Hepatocyte Growth Factor Activator Inhibitor-2 in the Regulation of Epithelial Matriptase Activity
Roman Szabo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma
J. M. Lucas et al.
JOURNAL OF PATHOLOGY (2008)
Roles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptase
Kenji Kojima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Roles and regulation of membrane-associated serine proteases
D. Qiu et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
The human airway trypsin-like protease modulates the urokinase receptor (uPAR, CD87) structure and functions
Nathalie Beaufort et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family
Otto J. P. Kyrieleis et al.
FEBS JOURNAL (2007)
Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the γ-subunit
James B. Bruns et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis
Xinlian Jin et al.
CANCER SCIENCE (2006)
Initiation of plasminogen activation on the surface of monocytes expressing the type II transmembrane serine protease matriptase
Lynette M. Kilpatrick et al.
BLOOD (2006)
Pro-urokinase-type plasminogen activator is a substrate for hepsin
Paul Moran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium
Eva Böttcher et al.
JOURNAL OF VIROLOGY (2006)
Secondary amides of sulfonylated 3-amidinophenylalanine.: New potent and selective inhibitors of matriptase
Torsten Steinmetzer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Orchitis: A complication of severe acute respiratory syndrome (SARS)
J Xu et al.
BIOLOGY OF REPRODUCTION (2006)
Influenza A virus (H5N1) infection in cats causes systemic disease with potential novel routes of virus spread within and between hosts
GF Rimmelzwaan et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF α-converting enzyme activity in airway epithelial cells
M Chokki et al.
FEBS JOURNAL (2005)
Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasin
B Fan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity
R Szabo et al.
BIOCHEMICAL JOURNAL (2005)
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
S Herter et al.
BIOCHEMICAL JOURNAL (2005)
Influenza: Lessons from past pandemics, warnings from current incidents
T Horimoto et al.
NATURE REVIEWS MICROBIOLOGY (2005)
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells
S Wilson et al.
BIOCHEMICAL JOURNAL (2005)
Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2
D Kirchhofer et al.
FEBS LETTERS (2005)
Regulation of prostasin expression and function in the prostate
LM Chen et al.
PROSTATE (2004)
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA)
BA Katz et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Biochemical characterization of prostasin, a channel activating protease
A Shipway et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes
JP Hobson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
WH Li et al.
NATURE (2003)
Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator Inhibitor-1B (HAI-1B), a new splice variant of HAI-1
D Kirchhofer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain
JR Somoza et al.
STRUCTURE (2003)
Serine protease mechanism and specificity
L Hedstrom
CHEMICAL REVIEWS (2002)
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro
M Guipponi et al.
HUMAN MOLECULAR GENETICS (2002)
Furin at the cutting edge: From protein traffic to embryogenesis and disease
G Thomas
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Regulation of the epithelial sodium channel by serine proteases in human airways
SH Donaldson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase
R Friedrich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Type II transmembrane serine proteases - Insights into an emerging class of cell surface proteolytic enzymes
JD Hooper et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease
SL Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates
T Takeuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
