4.7 Review

Understanding APE1 cellular functions by the structural preference of exonuclease activities

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Note: Only part of the references are listed.
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Summary: APE2 is recognized as an essential player in maintaining the integrity of the genome and epigenome. This review provides a comprehensive overview of APE2, including its functional domains, nuclease activities, interaction proteins, roles in various DNA repair pathways, and functions in growth, development, and diseases.

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