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An Overview of 2-Styrylchromones: Natural Occurrence, Synthesis, Reactivity and Biological Properties

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2017, Issue 22, Pages 3115-3133

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201700003

Keywords

Oxygen heterocycles; Chromones; 2-Styrylchromones; Synthetic methods; Reactivity; Biological activity

Funding

  1. Instituto Politecnico de Braganca
  2. University of Aveiro
  3. Formacion en Centros de Trabajo, Ministerio de Educacion y Ciencia (FCT, MEC) [FCT UID/QUI/00062/2013]
  4. Fundo Europeu De Desenvolvimento Regional (FEDER)

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2-Styrylchromones are a small class of oxygen-containing heterocycles. Despite their sparse occurrence in nature, several synthetic approaches have been developed in order to synthesize a large variety of derivatives, possessing different substituents in different positions of the main core. They are also versatile building blocks in the synthesis of new heterocyclic systems and important intermediates in the search for bioactive compounds. It is our intention in this review to give a general overview on the natural occurrence, synthesis, reactivity and biological properties of 2-styrylchromones, which were published up until 2016.

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