4.5 Article

C-C Bond Formation by Oxidative Ring-Opening Homocoupling of Cyclobutanols

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2017, Issue 6, Pages 1070-1073

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201601505

Keywords

C-C coupling; Homocoupling; Oxidation; Radical reactions; Small ring systems

Funding

  1. National Natural Science Foundation of China [21302073, 21402168]
  2. Fundamental Research Funds for the Central Universities [lzujbky-2016-53]
  3. Lanzhou University
  4. Recruitment Program of Global Experts

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The formation of a C(sp(3))-C(sp(3)) bond by oxidative ring-opening homocoupling of cyclobutanols was explored. A broad scope of 1-substituted cyclobutanols were transformed into C(sp(3))-C(sp(3)) bond-formation products by oxidative ring opening in good to high yields under exceptionally mild conditions in an open flask in just 30 s.

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