Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2017, Issue 34, Pages 5110-5118Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201700974
Keywords
Cyanides; Imidazoles; Synthesis design; Green chemistry
Categories
Funding
- National Health and Medical Research Council [APP1024314]
- Australian Government
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A straightforward and solvent-free synthesis of various secondary and tertiary cyanoformamides from carbamoyl imidazoles and TMSCN has been developed. Both cyclic and acyclic carbamoyl imidazoles react smoothly to form the relevant cyanoformamides in excellent yields, often within minutes.
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