Journal
MOLECULES
Volume 26, Issue 17, Pages -Publisher
MDPI
DOI: 10.3390/molecules26175377
Keywords
antioxidants; bioactive compounds; extraction methods; natural sources; structure
Funding
- Fundacao para a Ciencia a Tecnologia (FCT)
- Ministerio da Educacao e Ciencia
- FEDER [UI0183-UID/BIA/04004/2020, UIDB/50006/2020]
- FCT [SFRH/BPD/100865/2014]
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Flavonoids are natural antioxidants synthesized in plants, playing a crucial role in plant stress tolerance and human health with anti-inflammatory and antimicrobial properties. They also have various applications in the food industry, cosmetics, and pharmaceuticals. Developing extraction methods for flavonoids with high purity and yield is essential for their industrial use.
In recent years, more attention has been paid to natural sources of antioxidants. Flavonoids are natural substances synthesized in several parts of plants that exhibit a high antioxidant capacity. They are a large family, presenting several classes based on their basic structure. Flavonoids have the ability to control the accumulation of reactive oxygen species (ROS) via scavenger ROS when they are formed. Therefore, these antioxidant compounds have an important role in plant stress tolerance and a high relevance in human health, mainly due to their anti-inflammatory and antimicrobial properties. In addition, flavonoids have several applications in the food industry as preservatives, pigments, and antioxidants, as well as in other industries such as cosmetics and pharmaceuticals. However, flavonoids application for industrial purposes implies extraction processes with high purity and quality. Several methodologies have been developed aimed at increasing flavonoid extraction yield and being environmentally friendly. This review presents the most abundant natural flavonoids, their structure and chemical characteristics, extraction methods, and biological activity.
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