β-Cyclodextrin functionalized 3D reduced graphene oxide composite-based electrochemical sensor for the sensitive detection of dopamine

A three-dimensional reduced graphene oxide nanomaterial with beta-cyclodextrin modified glassy carbon electrode (3D-rGO/beta-CD/GCE) was constructed and used to detect the electrochemical behavior of dopamine (DA). The nanocomposite materials were characterized by scanning electron microscopy (SEM), infrared spectrometry (FT-IR), Raman spectrogram and thermogravimetric analysis (TGA), which showed that beta-CD was well modified on 3D graphene with a porous structure. The electrochemical properties of different modified electrodes were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), proving the highest electron transfer rate of the 3D-rGO/beta-CD modified electrode. The experimental conditions such as scan rate, pH, enrichment time and layer thickness were optimized. Under the best experimental conditions, DA was detected by differential pulse voltammetry (DPV) by 3D-rGO/beta-CD/GCE with excellent electrocatalytic ability and satisfactory recognition ability, resulting in a wide linear range of 0.5-100 mu M and a low detection limit (LOD) of 0.013 mu M. The modified electrode based on 3D-rGO/beta-CD nanocomposites is promising in the field of electrochemical sensors due to its high sensitivity and other excellent properties.

Automated summary

A three-dimensional reduced graphene oxide nanomaterial with beta-cyclodextrin modified glassy carbon electrode was constructed and used to detect the electrochemical behavior of dopamine. The nanocomposite materials were characterized and optimized, showing excellent electrocatalytic ability and sensitivity for dopamine detection, promising potential in the field of electrochemical sensors.