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Beta-glucans and cancer: The influence of inflammation and gut peptide

Journal

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 142, Issue -, Pages 486-492

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2017.09.013

Keywords

beta-Glucans; Inflammation; PYY; GLP-1; GLP-2; Ghrelin; Glucose; Insulin; Cancer

Funding

  1. Ministero dell'Istruzione, dell'Universita e della Ricerca, Italy

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Dietary beta-glucans are soluble fibers with potentially health-promoting effects. Gut peptides are important signals in the regulation of energy and glucose homeostasis. This article reviews the effects of different enriched beta-glucan food consumption on immune responses, inflammation, gut hormone and cancer. Gut hormones are influenced by enriched beta-glucan food consumption and levels of such peptide as YY, ghrelin, glucagon-like peptide 1 and 2 in humans influence serum glucose concentration as well as innate and adaptive immunity. Cancer cell development is also regulated by obesity and glucose dish-omeostasy that are influenced by beta-glucan food consumption that in turn regulated gut hormones. (C) 2017 Elsevier Masson SAS. All rights reserved.

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