Journal
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
Volume 66, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/ijph.2021.1604235
Keywords
children; air pollution; generalized additive model; dry eye disease; Shenzhen
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Funding
- Sanming Project of Medicine in Shenzhen [SZSM202011015]
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The study found significant associations between air pollution exposure and pediatric outpatient visits for dry eye disease, with NO2 and PM10 exposure having the most significant impact on the risk of dry eye disease.
Objectives: This study aimed to investigate the associations between air pollution exposure and pediatric outpatient visits for dry eye disease (DED) in Shenzhen, China. Methods: Generalized additive models were utilized to explore the acute effects of air pollution exposure on pediatric outpatient visits for DED. Results: Single-day lag exposures to NO2, O-3, PM2.5, and PM10 were associated with DED outpatient visits at lag days 0, 6, 4 and 2. Relative risks (RRs) for DED given a 10-mu g/m(3) increase in NO2, O-3, PM2.5, and PM10 concentrations were 1.062[95% confidence interval (CI) 1.003, 1.123], 1.015(95% CI 1.001, 1.031), 1.052(95% CI 1.001, 1.115), and 1.038 (95% CI 1.002, 1.076), respectively. RR for DED given a 10-mu g/m(3) increase in NO2 over cumulative lag days 0-1 was 1.075 (95% CI 1.009, 1.147), and RR for DED given a 10-mu g/m(3) increase in PM10 over cumulative lag days 0-4 was 1.051 (95% CI 1.003, 1.102). Conclusion: The observed associations between air pollution and outpatient visits for DED may provide evidence for policy makers to consider implementing measures to reduce the risk of DED owing to air pollution in China.
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