Journal
CHEMICAL COMMUNICATIONS
Volume 57, Issue 81, Pages 10572-10575Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1cc03838a
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Funding
- Danish National Research Foundation [DNRF124]
- Independent Research Fund Denmark (Green transition programme) [0217-00277A]
- Villum Foundation - Novo Nordisk Foundation [NNF 19OC0055825]
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The improved sensitivity of a suitable C-13 NMR approach allows for the observation of more extensive reaction networks, assay time windows, and relative flux measurements in living cells.
Insights into intracellular chemistry have remained sparse, but would be impactful for the advancement of biomedicine and bioproduction. A suitable C-13 NMR approach provides improvements in sensitivity that make extended reaction networks and assay time windows, previously inaccessible cell densities and relative flux measurements accessible in living cells.
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