4.7 Review

Hydrogel-based flexible materials for diabetes diagnosis, treatment, and management

Journal

NPJ FLEXIBLE ELECTRONICS
Volume 5, Issue 1, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41528-021-00122-y

Keywords

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Funding

  1. National Natural Science Foundation of China [52003224, 52073230, 61935017]
  2. Natural Science Basic Research Program of Shaanxi Province [2020GXLH-Z-013, 2019JQ-157, 2019KJXX-064]
  3. Projects of International Cooperation and Exchanges NSFC [51811530018]
  4. Ningbo Natural Science Foundation [202003N4051]
  5. Fundamental Research Funds for Central Universities
  6. Yulin Municipal Science and Technology Bureau
  7. Key Laboratory for Organic Electronics and Information Displays

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Hydrogels have unique advantages as flexible materials for diabetes management, including glucose monitoring, insulin delivery, and wound care. However, there are still challenges and issues that need to be addressed in the development of hydrogel-based flexible devices for personalized diabetes management.
Diabetes is a chronic metabolic disease characterized by high glucose concentration in blood. Conventional management of diabetes requires skin pricking and subcutaneous injection, causing physical pain and physiological issues to diabetic individuals. Hydrogels possess unique advantages such as lightweight, stretchability, biocompatibility, and biodegradability, offering the opportunities to be integrated as flexible devices for diabetes management. This review highlights the development of hydrogels as flexible materials for diabetes applications in glucose monitoring, insulin delivery, wound care, and cell transplantation in recent years. Challenges and prospects in the development of hydrogel-based flexible devices for personalized management of diabetes are discussed as well.

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