Journal
EUROPEAN JOURNAL OF HAEMATOLOGY
Volume 99, Issue 2, Pages 112-118Publisher
WILEY
DOI: 10.1111/ejh.12883
Keywords
5-azacitidine; infection; myelodysplastic syndromes supportive care; socioeconomics and ethics
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Myelodysplastic Syndromes are oligo-clonal stem cell disorders that are associated with cytopenias in the peripheral blood. Major causes for morbidity and mortality in myelodysplastic syndromes (MDS) patients are infections mostly due to bacteria or fungi. Beside leucopenia per se in affected patients, function of white blood cells particularly that of neutrophils seems to be impaired. Here we summarize the available data on infections in MDS patients in general and particularly those treated with 5-azacitidine.
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