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Translational biophotonics with Raman imaging: clinical applications and beyond

Journal

ANALYST
Volume 146, Issue 21, Pages 6379-6393

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d1an00954k

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Funding

  1. NIH [U54-CA22508]

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Raman scattering based technologies are continuously being developed to address challenges in diagnostic medicine, surgical guidance, therapeutic monitoring, and histopathology. The focus is on high-speed imaging methods that provide spatial context for translational biomedical applications.
Clinical medicine continues to seek novel rapid non-invasive tools capable of providing greater insight into disease progression and management. Raman scattering based technologies constitute a set of tools under continuing development to address outstanding challenges spanning diagnostic medicine, surgical guidance, therapeutic monitoring, and histopathology. Here we review the mechanisms and clinical applications of Raman scattering, specifically focusing on high-speed imaging methods that can provide spatial context for translational biomedical applications.

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