Journal
2021 IEEE 21ST INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE NANO 2021)
Volume -, Issue -, Pages 159-162Publisher
IEEE
DOI: 10.1109/NANO51122.2021.9514318
Keywords
creatinine; copper oxide; screen-printed carbon electrode; electrochemical analysis
Funding
- Chulalongkorn University Research Grant (Rachadapiseksompoj Grant) [CU_GR_63_37_21_05]
- Digital Economy and Society Development Funds (ONDE) [PR63031761]
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Creatinine, a metabolite in muscles, is excreted via urine and can indicate renal function, especially in patients with chronic kidney disease. A new portable screen-printed carbon electrode with copper oxide nanostructure has been developed for creatinine detection, showing linear responses in the range of 0-30 mM, providing a quick and reliable alternative for CRE detection.
Creatinine, a metabolized product of phosphocreatine in muscles, is excreted via urine by kidneys. Creatinine concentration in urine is an indicator of renal function for a patient with chronic kidney disease. A single-use and portable screen- printed carbon electrode with copper oxide nanostructure was developed for creatinine detection via copper-creatinine complex formation. SEM was deployed to visualize the copper oxide nanostructure. Creatinine measurement was performed in 0.1 M PBS at pH 6.5 with a smartphone application and portable near-field communication potentiostat. Five chemicals were tested as interferences. The CuO/SPCE shows linear and repeatable responses of creatinine from 0-30 mM, which makes it an appealing alternative for quick and reliable CRE detection.
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